Evaluating cardiac output measurement methods in critically ill patients on life support
Official title: Correlation of Cardiac Output Determined by Echocardiography and Indirect Calorimetry in Critically Ill Patients in Cardiogenic Shock on Extracorporeal Circulatory Life Support
Run by Universität Münster · NCT06369818 · Data updated 2026-11-12
This study is testing if a method that measures energy use can accurately estimate heart function in critically ill patients on life support.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Universität Münster Academic / other |
| Locations | 1 site (Münster) |
| Status | Recruiting |
| Started | January 18, 2024 |
| Main results expected | September 2026 |
| Study ends | February 2027 |
| Registry record updated | May 20, 2024 |
| Trial ID | NCT06369818 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have undergone cardiac surgery and require extracorporeal life support during the perioperative period.
✕Probably not a fit
Patients who are pregnant, breastfeeding, or have a dependency relationship with the study sponsor will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the correlation between cardiac output measured by indirect calorimetry and transthoracic echocardiography in critically ill patients experiencing cardiogenic shock who are on extracorporeal life support (ECLS). The study aims to determine if indirect calorimetry, a method typically used to assess energy expenditure, can reliably estimate cardiac output in these patients. By comparing these two measurement techniques, the research seeks to enhance the understanding of cardiac function during critical care. This could lead to improved monitoring and management strategies for patients in severe cardiac distress.
Why it matters
Potential benefit: If successful, this study could provide a more reliable method for assessing cardiac output in critically ill patients, potentially improving their treatment outcomes.
How similar studies have gone: While the correlation between indirect calorimetry and echocardiography in this specific context has not been conclusively established, similar studies have explored these methods in other critical care settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients that received cardiac surgery 2. Perioperative requirement of extracorporeal life support (ECLS) 3. Age ≥ 18 years 4. Informed consent Exclusion Criteria: 1. Pregnancy or breastfeeding 2. Relationship or dependency with the study sponsor 3. Expected survival less than 72 hours after screening
Where it's running
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University Hospital Münster
Münster, Germany Recruiting
Study contacts
- Principal investigator: Christian Ertmer, MD — University Hospital Muenster, Dept. of Anesthesiology, Intensive Care Therapy and Pain Medicine
- Study coordinator: Christian Ertmer, MD
- Email: christian.ertmer@ukmuenster.de
- Phone: +49-251-8347255
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.