Evaluating cardiac output measurement methods in critically ill patients on life support
Correlation of Cardiac Output Determined by Echocardiography and Indirect Calorimetry in Critically Ill Patients in Cardiogenic Shock on Extracorporeal Circulatory Life Support
This study is testing if a method that measures energy use can accurately estimate heart function in critically ill patients on life support.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universität Münster Academic / other |
| Locations | 1 site (Münster) |
| Trial ID | NCT06369818 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the correlation between cardiac output measured by indirect calorimetry and transthoracic echocardiography in critically ill patients experiencing cardiogenic shock who are on extracorporeal life support (ECLS). The study aims to determine if indirect calorimetry, a method typically used to assess energy expenditure, can reliably estimate cardiac output in these patients. By comparing these two measurement techniques, the research seeks to enhance the understanding of cardiac function during critical care. This could lead to improved monitoring and management strategies for patients in severe cardiac distress.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have undergone cardiac surgery and require extracorporeal life support during the perioperative period.
Not a fit: Patients who are pregnant, breastfeeding, or have a dependency relationship with the study sponsor will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more reliable method for assessing cardiac output in critically ill patients, potentially improving their treatment outcomes.
How similar studies have performed: While the correlation between indirect calorimetry and echocardiography in this specific context has not been conclusively established, similar studies have explored these methods in other critical care settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients that received cardiac surgery 2. Perioperative requirement of extracorporeal life support (ECLS) 3. Age ≥ 18 years 4. Informed consent Exclusion Criteria: 1. Pregnancy or breastfeeding 2. Relationship or dependency with the study sponsor 3. Expected survival less than 72 hours after screening
Where this trial is running
Münster
- University Hospital Münster — Münster, Germany (Recruiting)
Study contacts
- Principal investigator: Christian Ertmer, MD — University Hospital Muenster, Dept. of Anesthesiology, Intensive Care Therapy and Pain Medicine
- Study coordinator: Christian Ertmer, MD
- Email: christian.ertmer@ukmuenster.de
- Phone: +49-251-8347255
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.