Evaluating brain MRI features in patients with CASPR2 limbic encephalitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with autoimmune encephalitis associated with anti-CASPR2 antibodies. It aims to conduct a retrospective evaluation of brain MRI characteristics to understand their relationship with clinical outcomes. The study will analyze MRI records from patients who have tested positive for CASPR2 antibodies in their cerebrospinal fluid. By examining these MRI features, the research seeks to provide insights into the progression and manifestations of this rare neurological disorder.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a definite diagnosis of CASPR2-antibody-associated encephalitis
* available MRI records
* Ascertained positivity for CASPR2-antibodies in CSF

Exclusion Criteria:

* Positivity for another antibody against neural or glial antigens
* MRI images not available
* Not enough clinical data to ascertain outcome

Where it's running

• Hospices Civils de Lyon
  Bron, France Recruiting

Study contacts

• Study coordinator: Bastien Joubert, professor
• Email: Bastien.joubert@chu-lyon.fr
• Phone: +334 78 86 15 53

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.