Evaluating biomarkers for predicting outcomes in myocarditis patients
Risk Stratification Value of Biomarkers in Patients With Myocarditis (FORWARD): a National, Multicenter, Retrospective-prospective, Cohort Study
This study is trying to find out if certain biological markers can help predict how well patients with myocarditis will do over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 3 Years to 80 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06010199 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect clinical data and biological specimens from patients diagnosed with myocarditis to develop a predictive model for their prognosis. It involves both retrospective and prospective data collection, utilizing advanced techniques such as genome sequencing, transcriptome sequencing, and metabolomics analysis. The goal is to enhance understanding of myocarditis and improve risk stratification for affected patients.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with myocarditis who are regularly followed up at a cardiovascular center.
Not a fit: Patients outside the age range of 3 to 80 years, pregnant or lactating women, or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prognostic tools for myocarditis, allowing for more personalized treatment strategies.
How similar studies have performed: While there have been studies on myocarditis, the specific approach of using a comprehensive biomarker-based predictive model is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients should meet the diagnostic criteria for myocarditis * Patients who are regularly followed up at the corresponding cardiovascular center Exclusion Criteria: * Age \<3 years or \>80 years * Pregnant or lactating women * The patient refused to sign the informed consent and refused to participate in the study * None of the above is consistent, but the patient cannot sign the informed consent temporarily due to coma and other reasons, and there is no legal representative to sign it instead. Depending on the condition, the patient may not wake up to sign the informed consent
Where this trial is running
Xi'an, Shaanxi
- First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Principal investigator: Yang Yan — First Affiliated Hospital Xi'an Jiaotong University
- Study coordinator: Guoliang Li
- Email: liguoliang_med@163.com
- Phone: +8613759982523
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.