Evaluating anesthesia techniques for reducing inflammation in bariatric surgery
Modulation of the Inflammatory Response to Surgical Trauma: Comparison of Three Anesthetic Techniques in Bariatric Surgery Patients
This study tests different anesthesia methods during bariatric surgery to see which one helps reduce inflammation and supports better recovery for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Hospital HM Nou Delfos Academic / other |
| Locations | 1 site (Barcelona, Barcelona) |
| Trial ID | NCT06915558 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how different anesthesia methods impact inflammation in patients undergoing bariatric surgery. Participants will be randomly assigned to receive either opioid-free anesthesia, intravenous anesthesia with opioids, or inhalational anesthesia with opioids. Blood samples will be taken to measure inflammation-related substances and heart rate variability will be monitored to assess the body's stress response. The goal is to identify anesthesia strategies that may enhance recovery by modulating inflammation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a BMI of 30 kg/m² or higher, scheduled for elective bariatric surgery.
Not a fit: Patients who are pregnant, breastfeeding, or have chronic opioid use or severe comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery outcomes for patients undergoing bariatric surgery by minimizing inflammation.
How similar studies have performed: While the approach of using different anesthesia techniques is not entirely novel, the specific focus on inflammation modulation in bariatric surgery is relatively untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for bariatric surgery. * Age 18-65 years. * BMI ≥ 30 kg/m². * ASA physical status II-III. Exclusion Criteria: * Pregnancy or breastfeeding. * Chronic opioid use before surgery. * Severe renal or hepatic failure. * Uncontrolled psychiatric disorders. * Significant intraoperative complications requiring protocol deviation.
Where this trial is running
Barcelona, Barcelona
- Hospital HM Nou Delfos — Barcelona, Barcelona, Spain (Recruiting)
Study contacts
- Principal investigator: Gregory Contreras-Pérez, Anesthesiologist — Hospital HM Nou Delfos
- Study coordinator: Hipolito Labandeyra Gonzalez, Anesthesiologist
- Email: hipolitolabandeyra@gmail.com
- Phone: +34696055181
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.