Evaluating an online program for quitting smoking in rural areas
Official title: Addressing Rural Cancer Disparities Via Proactive Smoking Cessation Treatment Within Primary Care: A Hybrid Type 1 Effectiveness-Implementation Trial of a Scalable Smoking Cessation Electronic Visit
Run by Medical University of South Carolina · NCT05764759 · Data updated 2026-11-12
This study is testing an online program to help people in rural areas quit smoking and comparing it to regular care to see which works better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 288 (estimated) |
| Sponsor | Medical University of South Carolina Academic / other |
| Locations | 1 site (Charleston, South Carolina) |
| Status | Recruiting |
| Started | March 7, 2023 |
| Main results expected | February 28, 2027 |
| Study ends | August 15, 2027 |
| Registry record updated | March 5, 2026 |
| Trial ID | NCT05764759 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult smokers aged 18 and older who smoke at least one cigarette per day and are willing to engage with digital health tools.
✕Probably not a fit
Patients currently undergoing cessation treatment or using FDA-approved cessation medications within the last week will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research evaluates the effectiveness of an electronic visit (e-visit) designed for smoking cessation in rural primary care settings in South Carolina. Participants will be randomly assigned to either receive the e-visit, which includes a questionnaire about their smoking habits and preferences for cessation medications, or to receive standard care. The study will involve collecting questionnaires and breath samples at four different time points over a 24-week period. The trial aims to assess both the effectiveness of the e-visit and its implementation in these rural clinics.
Why it matters
Potential benefit: If successful, this intervention could provide a convenient and effective method for smokers in rural areas to quit smoking.
How similar studies have gone: Other studies have shown promise in using digital interventions for smoking cessation, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Current cigarette smoking, defined as smoking 1+ cigarettes per day, for 20+ days out of the last 30, for the last 6+ months * Age 18+ * Enrolled in Epic's MyChart program or willing to enroll * Possess a valid e-mail address that is checked daily to access study assessments and MyChart messages * Owner of an iOS or Android compatible smartphone to provide remote CO readings * Have a valid address at which mail can be received (for mailing iCO™) * English fluency Exclusion Criteria: \- Current engagement in cessation treatment, defined as use of an FDA-approved cessation medication within the last 7 days
Where it's running
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Medical University of South Carolina
Charleston, South Carolina, United States Recruiting
Study contacts
- Study coordinator: Noelle E Natale
- Email: natalen@musc.edu
- Phone: 843-876-9457
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.