Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Evaluating an online program for quitting smoking in rural areas

Official title: Addressing Rural Cancer Disparities Via Proactive Smoking Cessation Treatment Within Primary Care: A Hybrid Type 1 Effectiveness-Implementation Trial of a Scalable Smoking Cessation Electronic Visit

Run by Medical University of South Carolina · NCT05764759 · Data updated 2026-11-12

This study is testing an online program to help people in rural areas quit smoking and comparing it to regular care to see which works better.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment288 (estimated)
SponsorMedical University of South Carolina
Academic / other
Locations1 site (Charleston, South Carolina)
StatusRecruiting
StartedMarch 7, 2023
Main results expectedFebruary 28, 2027
Study endsAugust 15, 2027
Registry record updatedMarch 5, 2026
Trial IDNCT05764759 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult smokers aged 18 and older who smoke at least one cigarette per day and are willing to engage with digital health tools.

Probably not a fit

Patients currently undergoing cessation treatment or using FDA-approved cessation medications within the last week will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research evaluates the effectiveness of an electronic visit (e-visit) designed for smoking cessation in rural primary care settings in South Carolina. Participants will be randomly assigned to either receive the e-visit, which includes a questionnaire about their smoking habits and preferences for cessation medications, or to receive standard care. The study will involve collecting questionnaires and breath samples at four different time points over a 24-week period. The trial aims to assess both the effectiveness of the e-visit and its implementation in these rural clinics.

Why it matters

Potential benefit: If successful, this intervention could provide a convenient and effective method for smokers in rural areas to quit smoking.

How similar studies have gone: Other studies have shown promise in using digital interventions for smoking cessation, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Current cigarette smoking, defined as smoking 1+ cigarettes per day, for 20+ days out of the last 30, for the last 6+ months
* Age 18+
* Enrolled in Epic's MyChart program or willing to enroll
* Possess a valid e-mail address that is checked daily to access study assessments and MyChart messages
* Owner of an iOS or Android compatible smartphone to provide remote CO readings
* Have a valid address at which mail can be received (for mailing iCO™)
* English fluency

Exclusion Criteria:

\- Current engagement in cessation treatment, defined as use of an FDA-approved cessation medication within the last 7 days

Where it's running

  • Medical University of South Carolina
    Charleston, South Carolina, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.