Evaluating alpha-blocker therapy for managing urinary symptoms after prostate surgery
Official title: Management of Dysuria and Irritative Symptoms After HoLEP: a Prospective Study Evaluating the Efficacy of Alpha-Blocker Therapy
Run by Ankara Training and Research Hospital · NCT06865430 · Data updated 2026-11-12
This study is testing if the medication Tamsulosin can help men feel better by reducing painful and bothersome urinary symptoms after prostate surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 85 Years |
| Sex | Men only |
| Enrollment | 82 (estimated) |
| Sponsor | Ankara Training and Research Hospital Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | March 4, 2025 |
| Main results expected | September 4, 2025 |
| Study ends | March 4, 2026 |
| Registry record updated | March 24, 2025 |
| Trial ID | NCT06865430 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are men aged between 40 and 85 who have undergone HoLEP surgery.
✕Probably not a fit
Patients with prostate cancer, bladder stones, or a history of urethral stricture may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of alpha-blocker therapy, specifically Tamsulosin Hydrochloride, in alleviating dysuria and irritative urinary symptoms following Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic hyperplasia (BPH). It aims to address the common postoperative complications that affect patient quality of life, which occur in a significant percentage of patients within the first three months after surgery. By comparing the effects of the medication against a sham treatment, the study seeks to provide evidence on the potential benefits of alpha-blockers in this context.
Why it matters
Potential benefit: If successful, this study could significantly improve the management of postoperative urinary symptoms, enhancing patient satisfaction and quality of life.
How similar studies have gone: Previous studies have shown varying success with similar approaches, but this specific evaluation of alpha-blockers post-HoLEP is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Men over 40 years old, under 85 years old, and HoLEP surgery Exclusion Criteria: Prostate cancer, patients with bladder stones, patients with a history of urethral stricture, patients with detrusor underactivity in urodynamics, those who have had prostate surgery before
Where it's running
-
Ankara bilkent city hospital
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Kazım Ceviz
- Email: kazimmzz@hotmail.com
- Phone: 312 552 66 00
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Adaptive radiotherapy for localized prostate cancer
This study is testing a new type of radiation therapy for men with localized prostate cancer who have urinary problems to see if it can safely treat their cancer without causing too many side effects.
-
Bipolar TURP versus MOSES‑assisted Holmium laser enucleation for enlarged prostate
This trial will test whether MOSES‑assisted Holmium laser enucleation (MoLEP) or bipolar transurethral resection (Bi‑TURP) leads to shorter hospital stays and improved intraoperative outcomes for men with symptomatic benign prostatic hyperplasia and prostate volumes of 40–80 cc.
-
Comparing robotic and laser surgery for prostate enlargement treatment
This study is testing whether robotic surgery or laser surgery is better for treating men with prostate enlargement who haven't found relief from other treatments.
-
Comparing two treatments for benign prostatic hyperplasia
This study is testing whether a new procedure called Prostate Artery Embolization works better than the traditional surgery for treating enlarged prostate symptoms in men.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.