Evaluating advanced radiotherapy techniques for prostate cancer

Efficacy of Advanced Radiotherapy (ART) in Prostate Cancer Patients With Early Stage, Advanced, Metastatic and Relapsed Disease (PROST-ART)

Observational IRCCS San Raffaele · NCT06546267

This study is testing different advanced radiation treatments for prostate cancer to see how well they work and how they affect patients' lives.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages18 Years to 95 Years
SexMale
SponsorIRCCS San Raffaele Academic / other
Locations1 site (Milan)
Trial IDNCT06546267 on ClinicalTrials.gov

What this trial studies

This observational study analyzes the outcomes of various advanced radiotherapy techniques, including Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), and Stereotactic Body Radiotherapy (SBRT), in patients with different stages of prostate cancer. The study focuses on patients treated between 2004 and 2024, assessing their biochemical relapse-free survival, local and regional relapse rates, and overall survival. Additionally, it evaluates the acute and late toxicity of these treatments and includes a quality of life survey for participants who consent. The study aims to provide insights into the efficacy and safety of these advanced radiotherapy approaches.

Who should consider this trial

Good fit: Ideal candidates are prostate cancer patients over 18 years old who have undergone advanced radiotherapy techniques.

Not a fit: Patients with other tumors or those over 95 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve treatment strategies and outcomes for patients with prostate cancer.

How similar studies have performed: Other studies have shown promising results with advanced radiotherapy techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Prostate cancer patients, \> 18 years old, treated with IGRT, IMRT, SBRT

Exclusion Criteria:

* other tumors
* \> 95 years old

Where this trial is running

Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prostate CancerRadical RadiotherapyAdjuvant RadiotherapySalvage RadiotherapyStereotactic Body RadiotherapySimultaneous Integrated BoostOligometastatic DiseaseBone Metastases
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.