Evaluating a Probiotic Product for Weight Loss

Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy of a Probiotic Product in Weight Control

Not applicable Interventional Bioithas SL · NCT06815926

This study is testing whether a probiotic supplement can help people who are overweight or mildly obese lose weight over 12 weeks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment104 (estimated)
Ages18 Years and up
SexAll
SponsorBioithas SL Industry-sponsored
Locations1 site (Murcia)
Trial IDNCT06815926 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of a probiotic food supplement in reducing body weight among individuals with overweight and Grade I obesity. The study involves 104 volunteers who will participate in a randomized, double-blind, placebo-controlled design over a 12-week period, where participants will take either the probiotic or a placebo daily. The trial aims to explore the relationship between gut microbiota and weight management, contributing to the growing interest in probiotics as alternative treatments for obesity. Participants are required to maintain their lifestyle habits throughout the study.

Who should consider this trial

Good fit: Ideal candidates are men and women aged 18 and older with a BMI between 25.0 and 34.9 who are committed to maintaining their lifestyle during the study.

Not a fit: Patients with diabetes, serious pathologies, or those who have recently altered their lifestyle or taken weight loss medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a novel approach to weight management through the use of probiotics.

How similar studies have performed: Other studies have shown promising results with probiotics for weight management, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men and women aged ≥ 18 years.
* Body Mass Index (BMI) between 25.0 and 34.9 (overweight or obesity type I).
* Commitment to maintaining a lifestyle, including diet and sports habits, constant throughout the study.
* Signing of informed consent.

Exclusion Criteria:

* Subjects with diabetes (type I or II), hypothyroidism or other diseases that may promote weight gain.
* Presence of other serious pathologies, including cancer or autoimmune diseases, or any other that, at the medical discretion of the investigator, may influence the results of the study.
* Subjects who have participated in a weight loss program or who have substantially modified their lifestyle habits (diet, physical exercise) during the previous 3 months.
* Treatment with antibiotics in the previous 4 weeks.
* Consumption of products or drugs intended for weight loss or satiety control, or that may influence weight in the previous 4 weeks.
* Consumption of products containing probiotics in the previous 2 months.
* Contraindication to taking the product under investigation, or allergy or intolerance to any of its ingredients.
* In the case of women: pregnancy or breastfeeding, or plans to become pregnant during the course of the study.

Where this trial is running

Murcia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Overweight, Obesity Grade Iprobioticsoverweightobesityfood supplementgut microbiota
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.