Evaluating a new treatment for inflammatory bowel diseases using human intestinal models

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with ulcerative colitis and Crohn's disease who are under endoscopic surveillance to monitor their disease activity. The main goal is to assess the therapeutic potential of TREM-1 in treating inflammatory bowel diseases. Participants will undergo additional biopsies and blood sample collection to gather data on the treatment's effectiveness. The study aims to provide insights into how TREM-1 can influence disease management in these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients between 18 and 60 years
* Signed informed consent
* Ulcerative colitis (UC) patients with active disease
* Crohn's disease (CD) patients with active disease

Exclusion Criteria:

* UC or CD patients in remission
* Patients between 18 and 60 years without informed consent

Where it's running

• IRCCS San Raffaele
  Milan, Italy Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Long-Term Guselkumab Use in Adults with Inflammatory Bowel Disease

  This study looks at how long adults with Crohn's disease or ulcerative colitis stay on guselkumab in real-world care.

  Recruiting Janssen Research & Development, LLC · Amiens · NCT07822529

• Intestinal ultrasound-guided management for inflammatory bowel disease

  This study tests if adding point-of-care intestinal ultrasound at every visit changes treatment decisions for adults with Crohn’s disease or ulcerative colitis undergoing disease assessment.

  Recruiting Mahidol University · Bangkok · NCT07775352

• Resting energy use in kids with inflammatory bowel disease

  This multicenter study will test the resting energy expenditure of children aged 6–17 with new IBD diagnoses to see how it relates to disease activity and treatment.

  Recruiting Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · Alessandria, Piedmont · NCT07670975

• Active video education by disease subtype to improve bowel prep before colonoscopy

  We’re testing whether adding subtype-specific video education to standard prep improves bowel cleanliness in adults with IBD undergoing colonoscopy.

  Recruiting at 12 sites Xijing Hospital of Digestive Diseases · Beijing, BeijingBeijing and 11 other locations · NCT07582731

• Intestinal ultrasound to predict relapse in Crohn's disease patients in deep remission.

  This project will try to see if a noninvasive transabdominal ultrasound can predict relapses in adults with Crohn's disease who are currently in deep remission.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT07539727

• Ath-063: Testing a new treatment for moderately to severely active ulcerative colitis in patients who have tried other biologics

  This study tests ATH-063 to see if it helps people with moderate to severe ulcerative colitis who did not respond to or relapsed after prior biologic therapy.

  Recruiting at 4 sites Phase 2 Athos Therapeutics Inc · Miami, Florida and 3 other locations · NCT07513181

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.