Active video education by disease subtype to improve bowel prep before colonoscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter randomized trial enrolls 600 adults with ulcerative colitis or Crohn’s disease scheduled for colonoscopy and compares standard education plus subtype-specific video guidance to standard education alone. Participants are recruited from 13 centers in China and randomized 1:1, with stratification by center. The primary outcome is the Boston Bowel Preparation Scale score, and secondary outcomes include prep adequacy, procedure metrics, adherence, knowledge, adverse events, anxiety, and satisfaction. Outcome assessors are blinded to treatment assignment to reduce bias, and analyses will adjust for center effects. The intervention uses active video education delivered via smartphone before the procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age between 18 and 75 years, inclusive.
2. Confirmed diagnosis of Ulcerative Colitis (UC) or Crohn's disease (CD) according to standard clinical guidelines.
3. Scheduled for elective colonoscopy for IBD monitoring or disease activity assessment.
4. Able to understand written and verbal instructions and to use a smartphone to view video education materials.
5. Voluntary participation with written informed consent.

Exclusion Criteria:

1. Absolute contraindications to colonoscopy, including acute gastrointestinal perforation, fulminant colitis, toxic megacolon, or hemodynamic instability.
2. History of total or subtotal colectomy.
3. Acute or chronic intestinal obstruction.
4. Severe cardiac, pulmonary, hepatic, or renal insufficiency (eGFR \<30 mL/min/1.73m², NYHA class III/IV).
5. Severe psychiatric or cognitive impairment that prevents understanding of the study requirements.
6. Inability or unwillingness to provide written informed consent.
7. Pregnant or breastfeeding women.

Where it's running

• Peking Union Medical College Hospital
  Beijing, BeijingBeijing, China Recruiting
• Shengjing Hospital of China Medical University
  Shenyang, Liaoning, China Recruiting
• Affiliated Hospital of Qinghai University
  Xining, Qinghai, China Recruiting
• The Second Affiliated Hospital of Xi'an Jiaotong University
  Xi'an, Shaanxi, China Recruiting
• Air Force 986 Hospital
  Xi'an, Shaanxi, China Recruiting
• Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Jie Liang, MD, PhD
• Email: liangjie@fmmu.edu.cn
• Phone: 029-84771535

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.