ESPB vs. IV lidocaine for pain after breast reduction
Official title: Erector Spinae Plane Block (ESPB) Versus Intravenous Lidocaine Infusion for Postoperative Pain and Quality of Recovery in Patients Undergoing Breast Reduction Surgery: A Single Center, Prospective, Randomized Study.
Run by Centre of Postgraduate Medical Education · NCT07687069 · Data updated 2026-11-12
This study tests whether an ultrasound-guided erector spinae plane block plus intraoperative lidocaine helps reduce pain after breast reduction compared with intravenous lidocaine alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | Centre of Postgraduate Medical Education Academic / other |
| Locations | 1 site (Warsaw) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | July 2028 |
| Study ends | August 2028 |
| Registry record updated | October 9, 2026 |
| Trial ID | NCT07687069 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (ASA I–III) undergoing elective non-oncologic breast reduction who consent to participate.
✕Probably not a fit
Patients who do not respond to regional anesthesia or have contraindications to ESPB or lidocaine may not experience benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two analgesia approaches after elective breast reduction: an ultrasound-guided erector spinae plane block (ESPB) plus intraoperative lidocaine infusion versus standard care with intravenous lidocaine. It aims to see if ESPB can lower postoperative pain, lessen opioid use, and improve recovery within the first day after surgery. The trial targets adult patients with ASA I–III undergoing non-oncologic breast reduction and excludes those with chronic pain or certain comorbidities. Outcomes of interest include pain scores, analgesic consumption, and incidence of nausea and vomiting, aligned with multimodal analgesia principles in ERAS and PROSPECT guidelines.
Why it matters
Potential benefit: If successful, patients may experience less pain and opioid need after breast reduction, with quicker recovery and fewer opioid-related side effects.
How similar studies have gone: Prior prospective work suggests ESPB can reduce opioid use and pain after breast procedures, though the magnitude and clinical relevance can vary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA physical status I-III * Scheduled for elective breast reduction surgery for non-oncological indications Exclusion Criteria: * Refusal or inability to provide written informed consent * History of chronic somatic or neuropathic pain * Current psychiatric disorders or ongoing treatment with antidepressant medications * Poorly controlled cardiovascular disease * Known allergy or intolerance to amide local anesthetics, including lidocaine and bupivacaine * Current alcohol abuse or substance use disorder
Where it's running
-
Centre of Postgraduate Medical Education,Department of Anesthesia and Intensive Care
Warsaw, Poland Recruiting
Study contacts
- Study coordinator: Bartosz Horosz, MD,PhD
- Email: bartosz.horosz@gmail.com
- Phone: 0048225841122
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Validating patient-reported outcomes in breast reconstruction
This study is testing if certain questionnaires can accurately capture how patients feel after breast reconstruction surgery to help improve their care and outcomes.
-
Intraoperative Lidocaine or Dexmedetomidine to Help Postoperative Pain After Urethral Reconstruction
This study tests whether giving lidocaine or dexmedetomidine during urethral reconstruction can reduce pain after surgery and lower the chance of long-lasting pain.
-
New method for treating reflex syncope using cardioneuroablation
This study is testing a new heart treatment called cardioneuroablation to see which of three methods works best for finding the right spots in the heart to help people with severe fainting spells.
-
Treatment for reflex syncope using cardioneuroablation
This study is testing if a new procedure called cardioneuroablation can help people with severe reflex syncope by improving their heart function and reducing fainting episodes.
-
Bipolar ablation for treating ventricular arrhythmias after unipolar failure
This study is testing if a new type of heart procedure called bipolar ablation can help patients with heart rhythm problems who didn't get better from an earlier treatment.
-
Preventing infections after knee replacement surgery with vancomycin
This study is testing if using vancomycin during knee replacement surgery can help prevent infections after the operation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.