Enhanced care for early psychosis treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of enhanced coordinated specialty care (CSC 2.0) compared to standard CSC for individuals experiencing first-episode psychosis. Participants will either receive standard care or an enhanced version that includes additional support elements such as individual peer support, digital outreach, care coordination, multi-family group therapy, and cognitive remediation. The primary focus is to determine if these additional elements lead to increased engagement in treatment, measured by the number of clinic visits in the first year. The study will take place across several outpatient clinics in Massachusetts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* People undergoing an intake evaluation to CSC for first-episode psychosis in one of the following outpatient clinics:
* McLean Hospital OnTrack (OnTrack Clinic)
* Massachusetts General Hospital (FEPP Clinic)
* Boston Medical Center (WRAP Clinic)
* Cambridge Health Alliance (RISE Clinic)
* UMass Memorial Health Care (STEP Clinic)
* ServiceNet (PREP West)

Exclusion Criteria:

* None

Where it's running

• McLean Hospital OnTrack Clinic
  Belmont, Massachusetts, United States Recruiting
• Massachusetts General Hospital FEPP Clinic
  Boston, Massachusetts, United States Recruiting
• Boston Medical Center WRAP
  Boston, Massachusetts, United States Recruiting
• Cambridge Health Alliance RISE Clinic
  Cambridge, Massachusetts, United States Recruiting
• UMass Memorial Community Healthlink STEP Clinic
  Worcester, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Dost Ongur, MD, PhD — Mclean Hospital
• Study coordinator: Dost Ongur, MD, PhD
• Email: dongur@mgb.org
• Phone: 617-855-3922

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.