Effects of variable resistance training on neural adaptations
Neural Adaptations to Metronome-Paced Strength Training: Insights From Neuroscience and Human Movement Variability
This study is testing if adding different timing styles to strength training can improve muscle control and brain function in healthy adults aged 18 to 40.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Male |
| Sponsor | Egas Moniz - Cooperativa de Ensino Superior, CRL Academic / other |
| Locations | 1 site (Almada, Monte de Caparica) |
| Trial ID | NCT06532786 on ClinicalTrials.gov |
What this trial studies
This study investigates how incorporating variability into resistance training methods affects neural adaptations in the corticospinal tract and neuromuscular function. It aims to enhance motor control by using a metronome-paced strength training approach that includes fractal-like variability, which is often absent in traditional resistance training. The study will compare different pacing methods, including fractal paced, isochronous paced, and self-paced training, to assess their impact on muscle function and neural drive. Participants will be healthy adults aged 18 to 40, and the study will utilize techniques such as Transcranial Magnetic Stimulation to measure outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged between 18 and 40 years.
Not a fit: Patients with neurologic conditions, lower limb disabilities, or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved resistance training methods that enhance motor control and muscle function in healthy individuals.
How similar studies have performed: While the approach of incorporating variability in resistance training is innovative, similar studies have shown promise in enhancing motor control and neuromuscular function.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged between 18 and 40 years Exclusion Criteria: * Neurologic conditions; * Lower limb disabilities or disease; * Not able to provide informed consent; * Have an implanted device (e.g. pacemakers) or any metal in the body; * Medication advised against the application of Transcranial Magnetic Stimulation; * History/family history of seizures, brain lesions or head trauma, neurological or psychiatric diseases, epilepsy, migraine
Where this trial is running
Almada, Monte de Caparica
- Egas Moniz School of Health & Science — Almada, Monte de Caparica, Portugal (Recruiting)
Study contacts
- Study coordinator: João H Oliveira, MSc
- Email: joao.henriques.oliveira@gmail.com
- Phone: 913266232
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.