Clinical trial Recruiting at 2 sites Interventional Ages 18 to 59 Women only

Effect of time-restricted feeding on weight loss

Official title: Comparison of Weight Loss Induced by Daily Time-Restricted Feeding Versus Daily Caloric Restriction in Women With Overweight and Obesity

Run by Federal University of Minas Gerais · NCT03574103 · Data updated 2026-11-12

This study is testing if eating within specific time limits can help people lose weight better than just cutting calories without time restrictions.

Quick facts

Study typeInterventional
Ages18 Years to 59 Years
SexWomen only
Enrollment45 (estimated)
SponsorFederal University of Minas Gerais
Academic / other
Locations2 sites (Belo Horizonte, Minas Gerais and 1 other locations)
StatusRecruiting
StartedJuly 9, 2018
Main results expectedSeptember 2025
Study endsDecember 2026
Registry record updatedMarch 18, 2025
Trial IDNCT03574103 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are females aged 18 to 59 with a body mass index of 25 kg/m² or greater.

Probably not a fit

Patients with chronic health conditions, recent weight-loss surgeries, or those on specific medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of time-restricted feeding (TRF) as a dietary strategy for weight loss over an 8-week period. Participants will be divided into two groups: one receiving caloric restriction without time limits on feeding, and the other receiving caloric restriction with time limits. The TRF group will have options for meal timing, either starting at 8 a.m. or 12 p.m. All participants will follow a caloric restriction of 513 to 770 kcal based on their estimated energy requirements.

Why it matters

Potential benefit: If successful, this study could provide a new dietary approach for effective weight loss in overweight and obese individuals.

How similar studies have gone: Other studies have shown promising results with time-restricted feeding, suggesting potential effectiveness in weight management.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Females;
* Aged between 18 and 59 years old;
* Body mass index equal or greater 25 kg/m²;
* Agree to sign the informed consent.

Exclusion Criteria:

* Any chronic health conditions (e.g. chronic renal failure, autoimmune, heart, and liver disease);
* Thyroid diseases or medications for its treatment;
* Medications known to affect total energy expenditure;
* Use of steroids, immunosuppressants or non-steroidal anti-inflammatory drugs, weight-loss medications, oral hypoglycemic agents or insulin and any medications that influence metabolic and/or inflammatory parameters;
* Previous surgery for weight loss;
* Pregnancy or breast-feeding;
* Smoking;
* Alcohol use (\>2 doses/day).

Where it's running

  • Hospital da Clínicas
    Belo Horizonte, Minas Gerais, Brazil
    Recruiting
  • Hospital das Clínicas
    Belo Horizonte, Minas Gerais, Brazil
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.