Effect of time-restricted feeding on weight loss

Comparison of Weight Loss Induced by Daily Time-Restricted Feeding Versus Daily Caloric Restriction in Women With Overweight and Obesity

Not applicable Interventional Federal University of Minas Gerais · NCT03574103

This study is testing if eating within specific time limits can help people lose weight better than just cutting calories without time restrictions.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment45 (estimated)
Ages18 Years to 59 Years
SexFemale
SponsorFederal University of Minas Gerais Academic / other
Locations2 sites (Belo Horizonte, Minas Gerais and 1 other locations)
Trial IDNCT03574103 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of time-restricted feeding (TRF) as a dietary strategy for weight loss over an 8-week period. Participants will be divided into two groups: one receiving caloric restriction without time limits on feeding, and the other receiving caloric restriction with time limits. The TRF group will have options for meal timing, either starting at 8 a.m. or 12 p.m. All participants will follow a caloric restriction of 513 to 770 kcal based on their estimated energy requirements.

Who should consider this trial

Good fit: Ideal candidates are females aged 18 to 59 with a body mass index of 25 kg/m² or greater.

Not a fit: Patients with chronic health conditions, recent weight-loss surgeries, or those on specific medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new dietary approach for effective weight loss in overweight and obese individuals.

How similar studies have performed: Other studies have shown promising results with time-restricted feeding, suggesting potential effectiveness in weight management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Females;
* Aged between 18 and 59 years old;
* Body mass index equal or greater 25 kg/m²;
* Agree to sign the informed consent.

Exclusion Criteria:

* Any chronic health conditions (e.g. chronic renal failure, autoimmune, heart, and liver disease);
* Thyroid diseases or medications for its treatment;
* Medications known to affect total energy expenditure;
* Use of steroids, immunosuppressants or non-steroidal anti-inflammatory drugs, weight-loss medications, oral hypoglycemic agents or insulin and any medications that influence metabolic and/or inflammatory parameters;
* Previous surgery for weight loss;
* Pregnancy or breast-feeding;
* Smoking;
* Alcohol use (\>2 doses/day).

Where this trial is running

Belo Horizonte, Minas Gerais and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Overweight and ObesityObesityOverweightWeight lossFasting
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.