Effect of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners
Official title: Effects of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners: A Stratified Randomized Controlled Trial
Run by Paulista University · NCT06949995 · Data updated 2026-11-12
This study tests whether combining active recovery with blood flow restriction helps amateur runners recover after a run better than active recovery alone or resting.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Men only |
| Enrollment | 34 (estimated) |
| Sponsor | Paulista University Academic / other |
| Locations | 1 site (Presidente Prudente, São Paulo) |
| Status | Recruiting |
| Started | October 27, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | December 2026 |
| Registry record updated | October 15, 2026 |
| Trial ID | NCT06949995 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy male amateur runners aged 18–40 who run faster than 5:30 min/km and meet the exclusion criteria.
✕Probably not a fit
Participants with certain health conditions or risk factors that contraindicate exercise or thromboembolism risk may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In healthy amateur runners, the researchers compare three recovery strategies after a controlled exercise: active recovery with blood flow restriction (BFR), active recovery alone, and passive rest. They measure multiple recovery outcomes over 96 hours, including heart rate variability, muscle soreness, perceived recovery, perceived effort, cellular integrity, pain threshold, muscle properties, and both muscle power and aerobic capacity. Participants are 18–40 years old, male, and data are analyzed with repeated measures to see which approach supports faster and fuller recovery. This is a randomized, three-arm trial conducted at Paulista University with carefully standardized protocols and informed consent. Data will inform whether adding BFR to active recovery offers added benefits for post-exercise recovery in runners.
Why it matters
Potential benefit: If successful, the approach could improve recovery speed and quality for runners, potentially reducing downtime between training sessions.
How similar studies have gone: Prior research has shown benefits of active recovery and BFR separately; combining them is exploratory and not yet proven in this exact context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals who present one or more of the following characteristics will not be included: * 1 presence of any health condition that contraindicates or prevents exercise; * 2 diabetes and diagnosed high blood pressure; * 3 inflammatory, psychiatric, cardiovascular and/or respiratory rheumatological disease; - -4 being dependent on alcohol, consuming drugs and/or being a smoker; * 5 history of knee surgery (e.g., meniscal repair and ligament reconstruction) or recent lower limb musculoskeletal injury that may impair performance during tests or interventions (e.g., muscle injury, tendinopathy, patellofemoral pain and/or back pain column in the last six months); * 6 use of ergogenic supplements to improve physical performance and/or muscle mass and/or vasoactive medications; * 7 having one or more risk factors predisposing to thromboembolism Exclusion Criteria: * Participants will be excluded from the study if they: * 1 have a health problem that does not allow them to continue; * 2 wish to leave the study; * 3 not sign the consent form
Where it's running
-
Franciele Marques Vanderlei
Presidente Prudente, São Paulo, Brazil Recruiting
Study contacts
- Study coordinator: Franciele Marques Vanderlei, PhD
- Email: franmvanderlei@gmail.com
- Phone: +55 (18) 3229-5824
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.