Clinical trial Recruiting at 1 site Interventional Ages 18 to 40 Men only

Effect of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners

Official title: Effects of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners: A Stratified Randomized Controlled Trial

Run by Paulista University · NCT06949995 · Data updated 2026-11-12

This study tests whether combining active recovery with blood flow restriction helps amateur runners recover after a run better than active recovery alone or resting.

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Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexMen only
Enrollment34 (estimated)
SponsorPaulista University
Academic / other
Locations1 site (Presidente Prudente, São Paulo)
StatusRecruiting
StartedOctober 27, 2025
Main results expectedNovember 30, 2026
Study endsDecember 2026
Registry record updatedOctober 15, 2026
Trial IDNCT06949995 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy male amateur runners aged 18–40 who run faster than 5:30 min/km and meet the exclusion criteria.

Probably not a fit

Participants with certain health conditions or risk factors that contraindicate exercise or thromboembolism risk may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In healthy amateur runners, the researchers compare three recovery strategies after a controlled exercise: active recovery with blood flow restriction (BFR), active recovery alone, and passive rest. They measure multiple recovery outcomes over 96 hours, including heart rate variability, muscle soreness, perceived recovery, perceived effort, cellular integrity, pain threshold, muscle properties, and both muscle power and aerobic capacity. Participants are 18–40 years old, male, and data are analyzed with repeated measures to see which approach supports faster and fuller recovery. This is a randomized, three-arm trial conducted at Paulista University with carefully standardized protocols and informed consent. Data will inform whether adding BFR to active recovery offers added benefits for post-exercise recovery in runners.

Why it matters

Potential benefit: If successful, the approach could improve recovery speed and quality for runners, potentially reducing downtime between training sessions.

How similar studies have gone: Prior research has shown benefits of active recovery and BFR separately; combining them is exploratory and not yet proven in this exact context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals who present one or more of the following characteristics will not be included:
* 1 presence of any health condition that contraindicates or prevents exercise;
* 2 diabetes and diagnosed high blood pressure;
* 3 inflammatory, psychiatric, cardiovascular and/or respiratory rheumatological disease; - -4 being dependent on alcohol, consuming drugs and/or being a smoker;
* 5 history of knee surgery (e.g., meniscal repair and ligament reconstruction) or recent lower limb musculoskeletal injury that may impair performance during tests or interventions (e.g., muscle injury, tendinopathy, patellofemoral pain and/or back pain column in the last six months);
* 6 use of ergogenic supplements to improve physical performance and/or muscle mass and/or vasoactive medications;
* 7 having one or more risk factors predisposing to thromboembolism

Exclusion Criteria:

* Participants will be excluded from the study if they:
* 1 have a health problem that does not allow them to continue;
* 2 wish to leave the study;
* 3 not sign the consent form

Where it's running

  • Franciele Marques Vanderlei
    Presidente Prudente, São Paulo, Brazil
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.