How anesthesia type affects thinking after bariatric sleeve surgery
Official title: The Effects of Total Intravenous Anesthesia and Inhalational Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy
Run by Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · NCT07637357 · Data updated 2026-11-12
This observational study tests whether intravenous anesthesia or inhalational anesthesia leads to different cognitive outcomes after sleeve gastrectomy in adults with obesity.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Sancaktepe) |
| Status | Recruiting |
| Started | September 30, 2025 |
| Main results expected | April 30, 2026 |
| Study ends | July 30, 2026 |
| Registry record updated | June 9, 2026 |
| Trial ID | NCT07637357 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with BMI 35–50 kg/m2, ASA I–III, scheduled for first-time sleeve gastrectomy.
✕Probably not a fit
Patients with ASA IV or higher, significant kidney dysfunction, cardiac instability, or drug allergies may not experience cognitive benefits from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares two anesthesia approaches—total intravenous anesthesia (TIVA) and inhalational anesthesia—in adults aged 18 to 65 undergoing sleeve gastrectomy. Cognitive function will be assessed postoperatively using neurocognitive tests to see how the anesthesia method may influence recovery of mental sharpness. The goal is to determine which approach offers faster recovery, better comfort, and fewer cognitive changes, while observing residual drug effects. The study is conducted at a single hospital in Istanbul and includes adults with BMI 35–50 kg/m2, excluding those with significant comorbidities or drug allergies. Interventions are observational and focus on real-world use of anesthesia methods already in clinical practice.
Why it matters
Potential benefit: If successful, patients may experience quicker cognitive recovery and greater comfort with one anesthesia approach over the other.
How similar studies have gone: Previous work has explored cognitive outcomes after surgery with different anesthesia types, including non-cardiac procedures, but data in bariatric patients are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients of both sexes, Patients Aged between 18 and 65 years, Patients classified as ASA(American Society of Anesthesiologists) physical status I- III, Patients with a BMI (Body Mass Index) between 35 and 50 kg/m² scheduled to undergo sleeve gastrectomy as a type of bariatric surgery for the first time. Exclusion Criteria: Patients classified as ASA physical status 4 or high, Patients with known allergy to any of the drugs used in the study, Patients with bleeding disorders, Patients with serum creatinine levels \>2 mg/dL, Patients with severe arrhythmias and EF\<30%, Patients with a known history of drug abuse are excluded.
Where it's running
-
Şehit Prof. Dr. İlhan Varank Sancaktepe Training and Research Hospital
Istanbul, Sancaktepe, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Evin ERGÜN KASAP
- Email: evinergun341694@gmail.com
- Phone: +90216-606-33-00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.