Effect of a 21-day comprehensive spa program on female infertility

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-arm study conducted at a spa facility in Františkovy Lázně, Czech Republic, enrolling 55 women with infertility. Participants undergo a standardized 21-day spa program (KLP) alongside routine clinical care, with measurements taken before and after treatment. Primary outcomes are changes in hormonal markers (LH, FSH, prolactin, estradiol, progesterone, testosterone, AMH); secondary outcomes include body composition, psychometric assessments (PSS-10, EQ-5D-5L, FertiQoL), ultrasound parameters, and preliminary reproductive outcomes. The study does not modify the treatment protocol and aims to observe real-world effects of spa therapies on infertility-related parameters. Safety monitoring is aligned with standard clinical care at the spa facility.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female, age 20-40 years
* Diagnosis of infertility (primary or secondary)
* History of at least one unsuccessful embryo transfer

Exclusion Criteria:

* Contraindications to spa treatment
* Acute gynecological inflammation
* Severe comorbidities affecting study outcomes
* Oncological disease
* Alcohol intake \>20 g/day
* Non-compliance with treatment
* Diagnosed with endometriosis

Where it's running

• Spa Resort Pawlik-Aquaforum
  Františkovy Lázně, Carlsbad Region, Czechia Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.