E-IodoCal paste vs ZOE in primary molar pulpectomies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Sixty non-vital mandibular primary second molars in cooperative children aged 4–8 are randomly assigned to receive either E-IodoCal or ZOE as root canal obturation after standard chemo-mechanical preparation. Teeth are restored with stainless steel crowns and followed for 9 months with clinical and radiographic checks for pain, swelling, sinus tracts, mobility, and periapical radiolucencies. Outcomes are assessed at 3, 6, and 9 months to compare success rates between the two materials. The study uses a randomized controlled, split-mouth design to reduce patient-level variation. Primary aim is to determine if E-IodoCal provides comparable clinical and radiographic results to ZOE in pediatric pulpectomies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Clinical: -

* Healthy cooperative children with an age range of 4 - 8 years.
* Nonvital deep carious mandibular primary second molars with sufficient coronal structure and at least 2/3rd root structure intact.
* Pulp exposure where bleeding couldn't be stopped following removal of the coronal pulp tissue
* Previous history of irreversible pulpitis signs and symptoms as spontaneous pain, percussion sensitivity, fistulous tract related to the involved tooth, and pathologic tooth mobility (grade-I mobility)

Radiographic:

* Adequate alveolar bone support (coverage by the bone of minimum two- thirds of at least one root).
* Presence of interradicular radiolucency (discontinuity of lamina dura and/or furcation involvement less than or equal to half of the shortest root).

Exclusion Criteria:

Clinical:

* Non-restorable primary molars with severe mobility (greater than grade-I mobility).
* Children with systemic illness (any medically compromising condition).
* Primary molars beyond possible repair.

Radiographic:

* Extensive internal resorption.
* Extensive external pathological root resorption.
* Obliteration of the root canal.
* Physiological root resorption of more than a third of its length.

Where it's running

• faculty of dentistry, Tanta university
  Tanta, Egypt Recruiting

Study contacts

• Study coordinator: shaimaa eldesouky, assistant professor
• Email: shaimaaeldesouky@dent.tanta.edu.eg
• Phone: 01008994242

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.