Using pre-operative findings and AI to predict whether full pulpotomy will succeed in painful mature molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with mature permanent molars diagnosed with irreversible pulpitis will be enrolled and their pre-operative pulpal status classified using the AAE and Wolters systems. Digital radiographs will be taken to measure caries depth and to record any apical periodontitis, and an AI tool will analyze the X-rays for carious pulp exposure and apical changes. Participants will be randomly assigned to receive either full pulpotomy or conventional root canal treatment, with clinical and radiographic follow-up at 1, 3, and 6 months. The study will compare treatment outcomes and the AI software’s accuracy against clinical findings after caries removal.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Mature permanent molars with irreversible pulpitis.
* Presence of bleeding from all canals.
* The tooth is not periodontally compromised.

Exclusion Criteria:

* Non-vital teeth.
* Uncontrolled bleeding from any of the canals after ten minutes of application of hemostatic agent.
* Molars with immature roots.

Where it's running

• Misr International University (MIU)
  Cairo, Egypt Recruiting
• Misr International University
  Cairo, Egypt Recruiting

Study contacts

• Principal investigator: Mayand A Amer, B.D.S. — Misr International University
• Study coordinator: Mayand A Amer, B.D.S.
• Email: mayand.amer@miuegypt.edu.eg
• Phone: 01062509703

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.