Clinical trial Recruiting at 1 site Interventional Ages 60 and up

Dynamic versus isometric strength training for older adults with high blood pressure

Official title: Effects of Dynamic Strength Training and Isometric Strength Training on Cardiovascular Health Indicators, Mental Health, and Neuromuscular Fitness in Older Adults With Hypertension: A Feasibility Study

Run by University of Nove de Julho · NCT07448818 · Data updated 2026-11-12

This project will try dynamic and isometric strength exercises to see if they lower blood pressure and improve mental and muscle health in older adults with hypertension who take blood pressure medication.

Quick facts

Study typeInterventional
Ages60 Years and up
SexAll
Enrollment60 (estimated)
SponsorUniversity of Nove de Julho
Academic / other
Locations1 site (São Paulo, São Paulo)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedJune 30, 2027
Study endsDecember 31, 2027
Registry record updatedMay 1, 2026
Trial IDNCT07448818 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 60 or older with diagnosed arterial hypertension who are taking antihypertensive medication, have resting blood pressure below 160/95 mmHg, are not currently in a structured exercise program, and have no cognitive or functional limitations that prevent exercise.

Probably not a fit

People with uncontrolled or high‑risk cardiovascular conditions, active acute illnesses, decompensated clinical states, significant cognitive or functional impairments, or those already engaged in regular structured exercise may not benefit from or be eligible for this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized feasibility trial, people aged 60 and older with treated hypertension are assigned to supervised dynamic strength training, supervised isometric strength training, or a no-supervision control. Supervised exercise sessions are delivered at a single site in São Paulo with baseline and follow-up measures of blood pressure, cardiovascular indicators, neuromuscular fitness, and mental-health questionnaires. The study emphasizes safety, acceptability, and preliminary signals of benefit rather than definitive effectiveness. Results will inform whether a larger, definitive trial is warranted and which training approach appears most promising.

Why it matters

Potential benefit: If successful, the interventions could provide safe, low-cost exercise options that help lower blood pressure and improve strength and mental well-being in older adults.

How similar studies have gone: Previous studies have shown that resistance and isometric exercises can reduce blood pressure, though direct randomized comparisons specifically in older adults with hypertension are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Diagnosis of arterial hypertension and currently taking antihypertensive medication
* Age 60 years or older
* Resting blood pressure below 160/95 mmHg
* No high cardiovascular risk according to the American College of Sports Medicine criteria (for participants with type 2 diabetes, glycemic control with fasting glucose \<100 mg/dL and postprandial glucose \<140 mg/dL)
* Not participating in a structured exercise program for more than three months
* No cognitive or functional limitations that prevent participation in the exercise program

Exclusion Criteria

* Presence of acute illnesses, such as influenza, sinusitis, gastroenteritis, urinary tract infection, fever, inflammatory processes, or any clinical condition requiring rest or that may compromise safety during assessments or training.
* Decompensated clinical conditions, including: Blood pressure spikes, Chest pain, Uncontrolled arrhythmias, Shortness of breath at rest, Asthma exacerbations, Decompensated diabetes mellitus, characterized by Persistently elevated blood glucose levels (fasting glucose \> 180 mg/dL or postprandial glucose \> 250 mg/dL)
* Irregular use of medication
* Any unstable clinical condition or condition that represents additional risk for the practice of physical exercise.

Where it's running

  • Uninove
    São Paulo, São Paulo, Brazil
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.