Dome-only coiling for severe aneurysmal subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study will collect data on adults with CT-confirmed aneurysmal subarachnoid hemorrhage treated with the guideline-recommended dome-protection coiling approach at a single center. Eligible patients are those with an angiographically confirmed aneurysm and WFNS grade 3–5 who provide consent via a legally authorized representative within 72 hours of hemorrhage. The primary outcome is the incidence of aneurysm re-rupture within 90 days, censored at definitive aneurysm treatment or death and detected on surveillance head CT or after neurologic decline. Secondary outcomes include 90-day functional status and angiographic measures of dome protection success and procedural complications, and the protocol is observational without randomization.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years or older
* CT confirmed aSAH with an angiographically detected aneurysm
* World Federation of Neurological Sciences (WFNS) aSAH grade 3-5 aneurysm
* LAR available and gives consent within 72 hours after the onset of aSAH (or last known normal

Exclusion Criteria:

* Patients whose aneurysm judged appropriate for balloon-assisted coiling
* Patients whose aneurysm is bleeding from the "neck"
* Patients who are clinically judged to suffer imminent death within 24 hours.
* Pregnancy or positive urine pregnancy test

Where it's running

• University of Louisville Hospital
  Louisville, Kentucky, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.