Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Does the order of endurance and strength training in COPD rehab matter for muscle strength?

Official title: Effect of Intra-Session Training Order of Cardiorespiratory Endurance Work and Muscle Strengthening in COPD Patients

Run by CHU de Reims · NCT07655011 · Data updated 2026-11-12

This study tests whether doing strength training before endurance training during pulmonary rehab improves muscle strength in adults with COPD.

More Chronic Obstructive Pulmonary Disease (COPD) trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment138 (estimated)
SponsorCHU de Reims
Academic / other
Locations1 site (Reims)
StatusRecruiting
StartedAugust 6, 2026
Main results expectedAugust 2028
Study endsJanuary 2030
Registry record updatedSeptember 8, 2026
Trial IDNCT07655011 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with COPD (GOLD stages 2–4) admitted for pulmonary rehabilitation who can read and speak French.

Probably not a fit

Patients unable to participate in one of the training modalities or with contraindications to exercise may receive less or no additional benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates the effect of exercise order within a pulmonary rehabilitation session for adults with COPD. Participants will be assigned to either beginning with muscle strengthening or starting with endurance training in their rehab sessions. The trial focuses on practical exercise sequencing to see if the order influences muscle strength outcomes. It uses standard pulmonary rehab components and targets clinically relevant muscle function as a key endpoint. The setting is a COPD rehabilitation center in Reims, France, led by CHU de Reims.

Why it matters

Potential benefit: If successful, patients with COPD may experience greater gains in muscle strength from their rehabilitation sessions.

How similar studies have gone: Previous studies in healthy populations suggest the order of endurance and strength training can affect gains, but this COPD-specific approach is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* COPD GOLD stages 2 to 4
* Admitted for pulmonary rehabilitation in a participating center
* Ability to read and speak French
* Written informed consent
* Affiliation with a social security system

Exclusion Criteria:

* Legal protection (guardianship or trusteeship)
* Pregnancy beyond the second trimester
* Musculoskeletal disorders affecting lower limb strength or walking performance
* Vascular disease limiting walking distance
* Cardiac contraindication to pulmonary rehabilitation

Where it's running

  • Chu Reims
    Reims, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.