Do abdominal aneurysms occur in people who had a ruptured brain aneurysm
Official title: The Occurrence of Abdominal Aortic Aneurysms in Patients With Ruptured Intracranial Aneurysms
Run by Leiden University Medical Center · NCT07312565 · Data updated 2026-11-12
This study checks whether people who had a ruptured brain aneurysm also have an abdominal aortic aneurysm using an abdominal ultrasound.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 233 (estimated) |
| Sponsor | Leiden University Medical Center Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Leiden) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07312565 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) who have a confirmed IA-related SAH, are at least one year post-aSAH, and are enrolled in the SPARTA trial with informed consent.
✕Probably not a fit
Patients without an aSAH history or who do not meet SPARTA criteria are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective single-cohort study in patients with aneurysmal subarachnoid hemorrhage who will undergo an abdominal ultrasound to look for abdominal aortic aneurysms. The trial will collect data from multiple neurosurgical centers in the Netherlands and centralize analysis at Leiden University Medical Center. Participants are drawn from an existing prognosis study of acutely ruptured aneurysms and must be at least one year post-aSAH with informed consent. The objective is to better understand the co-occurrence of intracranial and abdominal aneurysms and to evaluate the potential need for routine AAA screening in this population.
Why it matters
Potential benefit: If an association is found, it could support targeted screening for abdominal aortic aneurysms in patients with aSAH to reduce morbidity and mortality.
How similar studies have gone: Prior literature suggests a possible association, but data are sparse and of variable quality, making this study somewhat exploratory but potentially informative.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: In order to be eligible to participate in this study, a participant must meet all of the following criteria: * Patient is a study subject of the trial: Study on Prognosis of Acutely RupTured Aneurysms (SPARTA)(12) * Inclusion at least one year after aSAH * Written informed consent By being a study subject of the SPARTA trial, the following criteria are applicable: * Confirmed diagnosis of SAH on CT-scan or lumbar puncture (in the presence of a negative CT-scan) * IA related SAH as confirmed with radiological imaging * Age 18 years or older at presentation * Written informed consent for the SPARTA-trial Exclusion Criteria: A potential participant who meets any of the following criteria will be excluded from participation in this study: * Patient is not a study subject of the SPARTA trial * Patient has Loeys-Dietz-, Marfan- or Ehlers-Danlos syndrome
Where it's running
-
Lumc
Leiden, Netherlands Recruiting
Study contacts
- Principal investigator: Jeroen Brouwers, MD, PhD — Leiden University Medical Centre
- Study coordinator: Alexander Hamming, MD
- Email: a.hamming@haaglandenmc.nl
- Phone: +31655322609
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Treatment of visceral aneurysms using flow diversion stents
This study is testing if using special stents can safely treat visceral aneurysms in patients and help improve their health over time.
-
Creating AI tools to predict vascular disease risk and progression
This study is trying to create smart computer tools that can predict the risk and progression of vascular diseases like abdominal aortic aneurysm and peripheral arterial disease by looking at medical images and patient history.
-
Cardiovascular Rehabilitation After Abdominal Aortic Aneurysm Repair
This study tests whether a structured cardiovascular rehabilitation program after abdominal aortic aneurysm repair leads to better fitness and quality of life than standard postoperative care.
-
Imaging inflammation in abdominal aortic aneurysm using a PET tracer
Researchers are testing whether a new PET tracer, 64Cu-DOTA-ECL1i, can image inflammation in an abdominal aortic aneurysm.
-
Poland–Italy Aortic Bridge Registry: PERCUTEK Tycheseal for Abdominal Aortic Aneurysm
This registry will see how well the PERCUTEK Tycheseal stent-graft works and how safe it is for adults having endovascular repair of abdominal aortic aneurysms.
-
PET scan to image MMP activity in abdominal aortic aneurysm
We will test whether a new PET tracer ([64Cu]-RYM2) can safely image MMP activity in people with abdominal aortic aneurysm and in healthy volunteers.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.