Digital tools to boost HPV vaccination intentions among Nigerian caregivers
Official title: A Randomized Trial of Digital Interventions to Increase HPV Vaccination Intentions Among Nigerian Caregivers
Run by University of Pennsylvania · NCT07498075 · Data updated 2026-11-12
This study tests whether different online content can help Nigerian parents of unvaccinated girls ages 9-14 decide to vaccinate their daughters against HPV.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 27 Years and up |
| Sex | All |
| Enrollment | 3340 (estimated) |
| Sponsor | University of Pennsylvania Academic / other |
| Locations | 1 site (Lagos) |
| Status | Recruiting |
| Started | May 7, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT07498075 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Parents or primary caregivers of at least one unvaccinated girl aged 9-14 years in Nigeria who are willing to participate online.
✕Probably not a fit
Parents whose beliefs or circumstances do not change with online messaging or who prefer non-digital information may not experience increased vaccination intention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares five digital content formats delivered online to Nigerian parents of unvaccinated girls aged 9-14. The goal is to see which approach most effectively increases parents' stated intention to have their daughters receive the HPV vaccine, measured immediately and after one week. Interventions include a motivational interviewing–style chatbot, a pre-bunking game against misinformation, short edutainment videos, standard informational infographics, and a control with unrelated health content. The study focuses on scalable, low-cost digital strategies that could be deployed via mobile phones and other online platforms. Primary findings will inform how best to tailor vaccine messaging to reduce parental hesitancy in this context.
Why it matters
Potential benefit: If successful, the study could identify digital messaging strategies that reliably increase parents' willingness to vaccinate their daughters against HPV.
How similar studies have gone: Prior digital health communication studies have shown mixed success; this trial tests several approaches to identify effective strategies in Nigeria.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Parent or primary caregiver of at least one girl aged 9-14 years * Parent states "no" or "unsure" to question asking if eligible daughter has received any doses of the HPV vaccine * Provides informed consent to participate Exclusion Criteria: * Parent or caregiver of a girl who has already received one or more doses of the HPV vaccine * Does not meet age eligibility criteria for an eligible daughter * Fails Attention Checks
Where it's running
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Online study
Lagos, Nigeria Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.