Clinical trial Recruiting at 1 site Interventional Ages 27 and up

Digital tools to boost HPV vaccination intentions among Nigerian caregivers

Official title: A Randomized Trial of Digital Interventions to Increase HPV Vaccination Intentions Among Nigerian Caregivers

Run by University of Pennsylvania · NCT07498075 · Data updated 2026-11-12

This study tests whether different online content can help Nigerian parents of unvaccinated girls ages 9-14 decide to vaccinate their daughters against HPV.

Quick facts

Study typeInterventional
Ages27 Years and up
SexAll
Enrollment3340 (estimated)
SponsorUniversity of Pennsylvania
Academic / other
Locations1 site (Lagos)
StatusRecruiting
StartedMay 7, 2026
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedJuly 16, 2026
Trial IDNCT07498075 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Parents or primary caregivers of at least one unvaccinated girl aged 9-14 years in Nigeria who are willing to participate online.

Probably not a fit

Parents whose beliefs or circumstances do not change with online messaging or who prefer non-digital information may not experience increased vaccination intention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares five digital content formats delivered online to Nigerian parents of unvaccinated girls aged 9-14. The goal is to see which approach most effectively increases parents' stated intention to have their daughters receive the HPV vaccine, measured immediately and after one week. Interventions include a motivational interviewing–style chatbot, a pre-bunking game against misinformation, short edutainment videos, standard informational infographics, and a control with unrelated health content. The study focuses on scalable, low-cost digital strategies that could be deployed via mobile phones and other online platforms. Primary findings will inform how best to tailor vaccine messaging to reduce parental hesitancy in this context.

Why it matters

Potential benefit: If successful, the study could identify digital messaging strategies that reliably increase parents' willingness to vaccinate their daughters against HPV.

How similar studies have gone: Prior digital health communication studies have shown mixed success; this trial tests several approaches to identify effective strategies in Nigeria.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parent or primary caregiver of at least one girl aged 9-14 years
* Parent states "no" or "unsure" to question asking if eligible daughter has received any doses of the HPV vaccine
* Provides informed consent to participate

Exclusion Criteria:

* Parent or caregiver of a girl who has already received one or more doses of the HPV vaccine
* Does not meet age eligibility criteria for an eligible daughter
* Fails Attention Checks

Where it's running

  • Online study
    Lagos, Nigeria
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.