Digital tool for identifying young people at risk of psychosis
Official title: E-Detection Tool for Emerging Mental Disorders
Run by King's College London · NCT05127278 · Data updated 2026-11-12
This study is testing a new online tool to help find young people aged 12-35 who might be at risk of developing psychosis so they can get early support.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 12 Years to 35 Years |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | King's College London Academic / other |
| Locations | 2 sites (Glasgow and 1 other locations) |
| Status | Recruiting |
| Started | April 20, 2022 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | November 29, 2024 |
| Trial ID | NCT05127278 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are young individuals aged 12-35 who have not previously experienced psychotic disorders.
✕Probably not a fit
Patients who are younger than 12 or older than 35, or those with existing psychotic disorders, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to develop an innovative E-Detection Tool for Emerging Mental Disorders (ENTER) to improve the identification of young individuals experiencing emerging psychosis. Participants aged 12-35 will complete an online questionnaire and short exercises on digital platforms, followed by face-to-face assessments to confirm their mental state. The tool will incorporate epidemiologically-based risk and protective factors to enhance the screening process, leveraging the research team's previous expertise in the field. The goal is to facilitate early detection and intervention for those at risk of psychosis.
Why it matters
Potential benefit: If successful, this tool could lead to earlier identification and intervention for young people at risk of developing psychosis, potentially improving their long-term mental health outcomes.
How similar studies have gone: Other studies have shown success with digital screening tools for mental health conditions, indicating potential for this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 12-35 years of age * Informed consent * Absence of previous psychotic disorders Exclusion Criteria: * \<12 or \>35 years of age * An existing psychotic disorder
Where it's running
-
Glasgow University
Glasgow, United Kingdom Recruiting -
King's College London
London, United Kingdom Recruiting
Study contacts
- Study coordinator: Paolo Fuasr Poli, MD PhD
- Email: paolo.fusar-poli@kcl.ac.uk
- Phone: +442078480900
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Examining the effects of combined therapy for schizophrenia
This study is testing whether combining two therapies, one for managing thoughts and another for improving cognitive skills, can help people with schizophrenia do better in their daily lives compared to using just one of the therapies.
-
State Representation in Early Psychosis 2
This observational study tests how people with early psychosis and healthy individuals use state information during tasks and how brain activity supports it.
-
Recovery-oriented suicide prevention for young people at clinical high risk for psychosis
This program tests a peer-supported, clinician-led suicide prevention group for young people at clinical high risk for psychosis to see if it helps reduce suicidal thoughts and support recovery.
-
Combined brain stimulation and yoga for improving cognition in psychosis
This study tests whether active brain stimulation plus yoga can improve thinking skills and daily function in adults with psychosis.
-
See if an early-detection program reduces time to treatment for first-episode psychosis
We test whether a large, region-wide early-detection program can shorten the time from first psychotic symptoms to treatment and help people function better later.
-
Cerebellar imaging markers to predict antipsychotic response in first-episode psychosis
This will test whether cerebellar brain scans can predict how people with first-episode psychosis respond to 12 weeks of treatment with risperidone or aripiprazole.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.