Diagnosing joint diseases using biomarkers from joint fluid and tissue

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect joint fluid or tissue samples from adults with bone and joint diseases to explore biomarkers from both conventional tests and newer methods like Raman spectroscopy. The study aims to see if these biomarkers can refine diagnoses and better classify patients who currently have unclear or unclassified rheumatic conditions. No intervention beyond sample collection is planned, and analysis will focus on diagnostic information from the specimens. Findings could improve early detection and inform treatment decisions in rheumatic diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Inflammatory and non-inflammatory bone and joint diseases requiring synovial fluid aspiration and/or joint replacement
* Collection of non-opposition
* Affiliated to or beneficiary of social security

Exclusion Criteria:

* Inability to speak and/or read French
* Neoadjuvant therapy
* Patients under tutor or curatorship
* Protected adults,
* Patients benefiting of State Medical Aid

Where it's running

• Service de Médecine Physique et de Réadaptation, Hôpital Cochin
  Paris, Idf, France Recruiting

Study contacts

• Principal investigator: Christelle Nguyen, MD, PhD — Service de Médecine Physique et de Réadaptation, Hôpital Cochin
• Study coordinator: Christelle Nguyen, MD, PhD
• Email: christelle.nguyen2@aphp.fr
• Phone: 00 33 1 58 41 29 45

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.