Detoxify for IVF: Cutting Everyday Pollutants to Help Infertility

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study provides a guide that explains common sources of environmental toxicants and practical steps to reduce exposure for people undergoing IVF. Researchers will assess understanding of the guide and how well participants maintain the recommended steps over time. They will measure levels of two classes of toxicants in urine, blood, and follicular fluid at baseline, mid-point, and after the intervention to see if exposure decreases in those with unexplained infertility planning IVF. The trial is conducted at the University of Iowa with collaboration from the American Society for Reproductive Medicine, led by Abigail Mancuso.

Why it matters

Who can join: the full rules

Inclusion criteria:

\- Unexplained infertility diagnosis (no identifiable male or female causes to infertility)

Exclusion criteria:

* Female age 38 years and older
* Male age 45 and older
* Diagnosis of diminished ovarian reserve
* Diagnosis of PCOS/PMOS
* Smoking or drug use in either male and/or female partner
* BMI \>40 in either partner
* Patients using donor oocytes/donor sperm/donor embryos

Where it's running

• University of Iowa
  Iowa City, Iowa, United States Recruiting

Study contacts

• Study coordinator: Abigail Mancuso, MD
• Email: abigail-mancuso@uiowa.edu
• Phone: 319-356-1767

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.