Carnitine and related supplements before IVF to see if they improve oocytes and embryos

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled study evaluates whether pre-IVF supplementation with L-carnitine, L-arginine, N-acetyl-L-carnitine, and myo-inositol can improve IVF outcomes. Participants are women aged 18-45 undergoing IVF at Narodni Front Clinic and are randomized to receive either the supplement combination for 12 weeks before oocyte retrieval or no supplementation. Outcomes include oocyte and embryo quality and subsequent biochemical and clinical pregnancy rates, assessed as part of routine IVF procedures. The study uses a sealed-envelope randomization method and compares baseline IVF results to those after the intervention to determine any added benefit. Safety monitoring focuses on standard IVF parameters and exclusion criteria exclude individuals with conditions that may confound results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* women undergoing IVF process
* women aged 18-45 years

Exclusion Criteria:

* obesity
* severe kidney disease
* liver insufficiency
* endocrine disorders
* the use of immunosuppressive medications

Where it's running

• Clinic for Gynecology and Obstetrics Narodni Front
  Belgrade, Savski Venac, Serbia Recruiting

Study contacts

• Study coordinator: Milan D PEROVIC, Ass. Prof., PhD
• Email: perovic.milan@gakfront.org
• Phone: +381644184953

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.