Daily lung ultrasound to see if it shortens hospital stays for adults with acute decompensated heart failure
Official title: HF-FOCUS: Serial Lung Ultrasound And Peripheral Venous Pressure Monitoring To Enhance The Care Of Hospitalized Patients With Acute Decompensated Heart Failure
Run by Mayo Clinic · NCT07572955 · Data updated 2026-11-12
This study tests whether daily lung ultrasound can shorten hospital stays and reduce readmissions for adults with acute decompensated heart failure.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Status | Recruiting |
| Started | August 26, 2026 |
| Main results expected | June 2028 |
| Study ends | June 2028 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07572955 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 and older admitted for acute decompensated heart failure at Mayo Clinic Rochester who consent to daily lung ultrasound examinations.
✕Probably not a fit
Some participants may not experience shorter hospital stays or reduced readmissions.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study looks at whether daily lung ultrasound examinations, performed during hospitalization, can shorten length of stay and lower the rate of recurrent heart failure hospitalizations compared with standard care. Eligible participants are adults admitted with various forms of acute or acute-on-chronic heart failure to the Mayo Clinic in Rochester. The trial compares daily ultrasound-guided assessments to a blinded standard of care arm, focusing on hospitalization efficiency and outcomes. Lung ultrasound is the primary intervention, with consent and daily procedures required during the hospital stay.
Why it matters
Potential benefit: If successful, patients may experience shorter hospital stays and fewer future heart failure hospitalizations.
How similar studies have gone: Previous work in ultrasound-guided management has shown potential benefits in heart failure care, but the specific daily lung ultrasound approach is still being evaluated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects ≥18 years of age * Admitted to St. Mary's Hospital Cardiology Progressive Care Unit (Cardiology 1-5 teams) * Admission diagnosis of either: 1. Acute systolic heart failure 2. Acute on chronic systolic heart failure 3. Acute diastolic heart failure 4. Acute on chronic diastolic heart failure 5. Acute right heart failure 6. Acute on chronic right heart failure 7. Failure heart biventricular * Able to provide informed consent and willing to undergo daily lung ultrasound examinations during their hospitalization. Exclusion Criteria: * Subjects \<18 years of age * Unable to provide informed consent. * Unwilling to undergo daily lung ultrasound examinations.
Where it's running
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Mayo Clinic in Rochester
Rochester, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Jared Bird, MD — Mayo Clinic
- Study coordinator: Andy Dang
- Email: dang.phong@mayo.edu
- Phone: 507-255-7752
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.