Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Daily lung ultrasound to see if it shortens hospital stays for adults with acute decompensated heart failure

Official title: HF-FOCUS: Serial Lung Ultrasound And Peripheral Venous Pressure Monitoring To Enhance The Care Of Hospitalized Patients With Acute Decompensated Heart Failure

Run by Mayo Clinic · NCT07572955 · Data updated 2026-11-12

This study tests whether daily lung ultrasound can shorten hospital stays and reduce readmissions for adults with acute decompensated heart failure.

More Acute Decompensated Heart Failure trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedAugust 26, 2026
Main results expectedJune 2028
Study endsJune 2028
Registry record updatedSeptember 8, 2026
Trial IDNCT07572955 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older admitted for acute decompensated heart failure at Mayo Clinic Rochester who consent to daily lung ultrasound examinations.

Probably not a fit

Some participants may not experience shorter hospital stays or reduced readmissions.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study looks at whether daily lung ultrasound examinations, performed during hospitalization, can shorten length of stay and lower the rate of recurrent heart failure hospitalizations compared with standard care. Eligible participants are adults admitted with various forms of acute or acute-on-chronic heart failure to the Mayo Clinic in Rochester. The trial compares daily ultrasound-guided assessments to a blinded standard of care arm, focusing on hospitalization efficiency and outcomes. Lung ultrasound is the primary intervention, with consent and daily procedures required during the hospital stay.

Why it matters

Potential benefit: If successful, patients may experience shorter hospital stays and fewer future heart failure hospitalizations.

How similar studies have gone: Previous work in ultrasound-guided management has shown potential benefits in heart failure care, but the specific daily lung ultrasound approach is still being evaluated.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects ≥18 years of age
* Admitted to St. Mary's Hospital Cardiology Progressive Care Unit (Cardiology 1-5 teams)
* Admission diagnosis of either:

  1. Acute systolic heart failure
  2. Acute on chronic systolic heart failure
  3. Acute diastolic heart failure
  4. Acute on chronic diastolic heart failure
  5. Acute right heart failure
  6. Acute on chronic right heart failure
  7. Failure heart biventricular
* Able to provide informed consent and willing to undergo daily lung ultrasound examinations during their hospitalization.

Exclusion Criteria:

* Subjects \<18 years of age
* Unable to provide informed consent.
* Unwilling to undergo daily lung ultrasound examinations.

Where it's running

  • Mayo Clinic in Rochester
    Rochester, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.