Using ultrasound to guide treatment for heart failure patients
Official title: A Parallel-group, Single-center, Two-arm Treatment Study to Assess the Safety and Effectiveness of Venous Ultrasound Guided Decongestion in Adult Patients Hospitalized with Acute Decompensated Heart Failure.
Run by Oslo University Hospital · NCT06714409 · Data updated 2026-11-12
This study is testing if using ultrasound to guide treatment can help hospitalized heart failure patients feel better by managing fluid buildup in their bodies.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 180 (estimated) |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo) |
| Status | Recruiting |
| Started | September 16, 2024 |
| Main results expected | October 1, 2025 |
| Study ends | October 1, 2025 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT06714409 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are hospitalized with a clinical diagnosis of acute decompensated heart failure and have elevated Pro-BNP levels.
✕Probably not a fit
Patients with medical or psychiatric conditions that prevent participation in the study may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the feasibility, safety, and effectiveness of using venous ultrasound (VExUS) to guide organ decongestion in patients hospitalized with acute decompensated heart failure (ADHF). A total of 180 patients will be randomly assigned to either the VExUS intervention group, where treatment decisions are informed by ultrasound results, or a standard of care group, where no such information is provided. The study aims to determine if VExUS can help manage venous congestion, a potential risk factor in ADHF. Participants will be monitored every other day during hospitalization, with follow-up assessments conducted six months post-discharge.
Why it matters
Potential benefit: If successful, this approach could lead to improved treatment outcomes for patients with acute decompensated heart failure.
How similar studies have gone: While the use of ultrasound in managing heart failure is gaining interest, this specific approach using VExUS is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or above * Admitted the ward of Department of Cardiology OUH Ullevål with a clinical diagnosis of ADHFdefined by European Society of Cardiology * Pro-BNP \> 800 ng/l at first day of admission * Capable of giving signed informed consent Exclusion Criteria: \- Any medical or psychiatric condition which in the opinion of the investigatorprecludes participation
Where it's running
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Department of Nephrology, Oslo University Hospital
Oslo, Norway Recruiting
Study contacts
- Study coordinator: Bård Waldum-Grevbo, MD, PhD
- Email: uxwabr@ous-hf.no
- Phone: +4722119220
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.