Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using ultrasound to guide treatment for heart failure patients

Official title: A Parallel-group, Single-center, Two-arm Treatment Study to Assess the Safety and Effectiveness of Venous Ultrasound Guided Decongestion in Adult Patients Hospitalized with Acute Decompensated Heart Failure.

Run by Oslo University Hospital · NCT06714409 · Data updated 2026-11-12

This study is testing if using ultrasound to guide treatment can help hospitalized heart failure patients feel better by managing fluid buildup in their bodies.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment180 (estimated)
SponsorOslo University Hospital
Academic / other
Locations1 site (Oslo)
StatusRecruiting
StartedSeptember 16, 2024
Main results expectedOctober 1, 2025
Study endsOctober 1, 2025
Registry record updatedDecember 3, 2024
Trial IDNCT06714409 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are hospitalized with a clinical diagnosis of acute decompensated heart failure and have elevated Pro-BNP levels.

Probably not a fit

Patients with medical or psychiatric conditions that prevent participation in the study may not benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the feasibility, safety, and effectiveness of using venous ultrasound (VExUS) to guide organ decongestion in patients hospitalized with acute decompensated heart failure (ADHF). A total of 180 patients will be randomly assigned to either the VExUS intervention group, where treatment decisions are informed by ultrasound results, or a standard of care group, where no such information is provided. The study aims to determine if VExUS can help manage venous congestion, a potential risk factor in ADHF. Participants will be monitored every other day during hospitalization, with follow-up assessments conducted six months post-discharge.

Why it matters

Potential benefit: If successful, this approach could lead to improved treatment outcomes for patients with acute decompensated heart failure.

How similar studies have gone: While the use of ultrasound in managing heart failure is gaining interest, this specific approach using VExUS is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or above
* Admitted the ward of Department of Cardiology OUH Ullevål with a clinical diagnosis of ADHFdefined by European Society of Cardiology
* Pro-BNP \> 800 ng/l at first day of admission
* Capable of giving signed informed consent

Exclusion Criteria:

\- Any medical or psychiatric condition which in the opinion of the investigatorprecludes participation

Where it's running

  • Department of Nephrology, Oslo University Hospital
    Oslo, Norway
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.