Custom patient-specific plates to correct a tilted upper jaw
Official title: Assessment of the Accuracy of Patient Specific Plates for Correction of Maxillary Cant in Facial Asymmetry: A Prospective Clinical Trial
Run by Cairo University · NCT07001826 · Data updated 2026-11-12
This project will test whether custom-made plates created from CT-based virtual surgical planning can better correct a tilted upper jaw in adults with facial asymmetry.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 8 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | June 11, 2025 |
| Trial ID | NCT07001826 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with a diagnosed maxillary cant and facial asymmetry who are candidates for orthognathic correction and meet inclusion/exclusion criteria are appropriate for this project.
✕Probably not a fit
People with craniofacial syndromes, a history of maxillofacial tumors or facial trauma, or cleft lip/palate are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, single-arm clinical project enrolling eight adults with maxillary cant and facial asymmetry who will undergo high-resolution CT imaging and 3D virtual surgical planning. Custom patient-specific titanium plates and cutting guides will be designed from the virtual plan and used during LeFort I osteotomy to reposition the maxilla. Postoperative CT scans will be compared to the preoperative virtual plan to quantify how closely the surgical result matches the planned correction, and participants will report satisfaction with appearance. Participants will be followed for up to six months to monitor healing and outcomes.
Why it matters
Potential benefit: If successful, using patient-specific plates could achieve more precise jaw alignment and more predictable cosmetic and functional results.
How similar studies have gone: Virtual surgical planning and patient-specific plates have been used in orthognathic surgery with reported improvements in accuracy, but prospective data specifically targeting maxillary cant are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age \> 18 years Presence of maxillary cant Presence of facial asymmetry Exclusion Criteria: Diagnosis of craniofacial syndrome History of maxillofacial tumors History of facial trauma Presence of cleft lip and/or palate
Where it's running
-
Faculty of Dentistry, Cairo University
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: abdulqadr M al-hawaagi, M.Sc. — Cario
- Study coordinator: abdulqadr M al-hawaagi, M.Sc.
- Email: abdulqader.alhawaagi@dentistry.cu.edu.eg
- Phone: +201092265426
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.