Custom patient-specific plates to correct a tilted upper jaw

Assessment of the Accuracy of Patient Specific Plates for Correction of Maxillary Cant in Facial Asymmetry: A Prospective Clinical Trial

Not applicable Interventional Cairo University · NCT07001826

This project will test whether custom-made plates created from CT-based virtual surgical planning can better correct a tilted upper jaw in adults with facial asymmetry.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment8 (estimated)
Ages18 Years and up
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT07001826 on ClinicalTrials.gov

What this trial studies

This is a prospective, single-arm clinical project enrolling eight adults with maxillary cant and facial asymmetry who will undergo high-resolution CT imaging and 3D virtual surgical planning. Custom patient-specific titanium plates and cutting guides will be designed from the virtual plan and used during LeFort I osteotomy to reposition the maxilla. Postoperative CT scans will be compared to the preoperative virtual plan to quantify how closely the surgical result matches the planned correction, and participants will report satisfaction with appearance. Participants will be followed for up to six months to monitor healing and outcomes.

Who should consider this trial

Good fit: Adults over 18 with a diagnosed maxillary cant and facial asymmetry who are candidates for orthognathic correction and meet inclusion/exclusion criteria are appropriate for this project.

Not a fit: People with craniofacial syndromes, a history of maxillofacial tumors or facial trauma, or cleft lip/palate are excluded and unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, using patient-specific plates could achieve more precise jaw alignment and more predictable cosmetic and functional results.

How similar studies have performed: Virtual surgical planning and patient-specific plates have been used in orthognathic surgery with reported improvements in accuracy, but prospective data specifically targeting maxillary cant are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age \> 18 years

Presence of maxillary cant

Presence of facial asymmetry

Exclusion Criteria:

Diagnosis of craniofacial syndrome

History of maxillofacial tumors

History of facial trauma

Presence of cleft lip and/or palate

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Facial AsymmetryHigh-resolution CT scansComputer-aided designVirtual surgical planningOrthognathic surgeryAsymmetrical mandibular deformitiesMaxillary cantLeFort I osteotomy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.