Patient-specific 3D-printed titanium implants for facial reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates the safety and performance of patient-specific titanium implants created with CAD and 3D printing for facial reconstruction. Eligible adults with facial bone defects or deformities will undergo preoperative imaging, implant design, and surgical placement following standard maxillofacial protocols. Postoperative follow-up will measure implant fit, stability, functional outcomes, complications, and patient satisfaction to determine if the approach provides improved symmetry and aesthetics. Outcomes will be assessed through clinical exams and patient-reported measures over a defined observation period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older.
* Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.
* Acquired or congenital facial deformities associated with bony defects or facial asymmetry.
* Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.
* Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).
* Ability to provide written informed consent.

Exclusion Criteria:

* Active pathological lesions at the time of enrollment.
* Age below 18 years.
* History of radiotherapy within 12 months prior to enrollment.
* Chronic untreated vitamin D deficiency.
* Uncontrolled diabetes mellitus.
* Inability or unwillingness to comply with follow-up requirements.

Where it's running

• Ahmad Fayez Ahmad
  Latakia, Syria Recruiting

Study contacts

• Study coordinator: Ahmad F Ahmad, Phd
• Email: ahmad.fayez.ahmad@latakia-univ.edu.sy
• Phone: 00963992035690

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.