Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Core exercises for treating knee pain

Official title: Effect of Adding Core Exercises to Hip and Knee-focused Exercises on Patellofemoral Pain Syndrome

Run by Cairo University · NCT06758050 · Data updated 2026-11-12

This study is testing if adding core strengthening exercises to regular physical therapy can help young adults with knee pain feel better and improve their strength and balance.

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment44 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Giza)
StatusRecruiting
StartedAugust 4, 2024
Main results expectedJanuary 15, 2025
Study endsJanuary 30, 2025
Registry record updatedJanuary 3, 2025
Trial IDNCT06758050 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 18 to 35 with chronic knee pain lasting over 12 weeks and specific aggravating activities.

Probably not a fit

Patients with a history of traumatic knee injuries or other significant knee pathologies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study aims to investigate the impact of core strengthening exercises on pain, strength, function, and balance in patients suffering from patellofemoral pain syndrome (PFPS). A total of 44 participants aged 18 to 35 will be divided into two groups: one receiving conventional physical therapy along with core exercises, and the other receiving only conventional therapy. The study will assess outcomes using various tools, including a Visual Analogue Scale and balance assessments, over a period of six weeks. The goal is to determine whether core strengthening can improve symptoms and functionality in individuals with PFPS.

Why it matters

Potential benefit: If successful, this approach could significantly reduce pain and improve function for patients with patellofemoral pain syndrome.

How similar studies have gone: Previous studies have shown promising results with similar core strengthening approaches for knee pain, suggesting potential for success in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients of both genders with an age range of 18- 35 years old.
2. Gradual development of pain in the front of the knee lasting more than 12 weeks.
3. Patients with body mass index 18- 25 kg m2.
4. Pain is aggravated by at least 2 of the following activities: jumping, running, prolonged sitting, stair climbing, kneeling, and squatting.

   1. Positive patellar grinding test.
   2. Insidious onset of symptoms, unrelated to a traumatic damage.

Exclusion Criteria:

1. Traumatic patellar subluxation or dislocation.
2. A history of any of the following conditions: meniscal or other intra articular pathologic conditions; cruciate or collateral ligament involvement.
3. Any lower limb bony or congenital deformities.
4. Previous knee and hip joint surgeries.
5. Osteoarthritis in the ankle, knee, or hip joints.
6. Conditions that affect muscle strength such as diabetes mellitus or rheumatoid arthritis.

Where it's running

  • Cairo University
    Giza, Egypt
    Recruiting

Study contacts

  • Principal investigator: rana ibrahim ahmed, Bachelor Physical Therapy-MUST — Misr University for Science and Technology
  • Study coordinator: Rana Ibrahim Ahmed, Bachelor Physical Therapy-MUST
  • Email: ranaibrahim066@gmail.com
  • Phone: 01151082787

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.