Popliteus muscle release versus Kinesio taping for patellofemoral pain
Official title: Popliteus Muscle Release Versus Kinesio Taping on Patellofemoral Pain Syndrome
Run by Cairo University · NCT07290296 · Data updated 2026-11-12
This will test whether popliteus muscle release or Kinesio taping better reduces pain and improves function in adults 18–30 with patellofemoral pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 10, 2026 |
| Main results expected | May 2026 |
| Study ends | May 2026 |
| Registry record updated | May 28, 2026 |
| Trial ID | NCT07290296 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 18–30 with at least three months of patellofemoral pain, worst-week pain ≥3/10, pain reproducible by activities like stairs or squatting, and a positive patellar compression or palpation test.
✕Probably not a fit
Patients with other specific knee pathology on imaging (osteoarthritis, meniscal, ligament, or cartilage injury), recurrent patellar dislocation, prior knee surgery, recent physiotherapy for patellofemoral pain syndrome, prolonged corticosteroid use, or acute knee trauma are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 18–30 with at least three months of patellofemoral pain and a minimum worst-week pain score of 3/10 will be enrolled. Participants will receive one of three interventions—popliteus muscle release, Kinesio taping, or standard physical therapy—and outcomes will include pain intensity, knee function, dynamic balance, and quadriceps strength. Pain will be measured with a visual analog scale and function, balance, and strength with standardized clinical and performance tests. The trial compares the short-term effects of a targeted soft-tissue release versus supportive taping when added to conventional care.
Why it matters
Potential benefit: If successful, the findings could identify a simple, non-surgical technique that reduces anterior knee pain and improves strength and balance.
How similar studies have gone: Systematic reviews suggest Kinesio taping can reduce pain as an adjunct to exercise and some reports support soft-tissue manipulation for knee pain, but direct head-to-head comparisons of popliteus release and taping are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of both genders with an age range of 18-30 years old. * minimum 3-month history of patellofemoral pain. * a pain score for worst pain intensity during the previous week of 3 or more on a Visual Analog Scale (0-10, most pain). * reproduced by at least two of the following activities: Stair ascent or descent, hopping, running, prolonged sitting, squatting, or kneeling and present on at least one of the following clinical tests: Compression of the patella or palpation of the patellar facets. Exclusion Criteria: * Clinical, x-ray, or MRI findings indicative of other specific pathology, including osteoarthritis, meniscal, ligament, or cartilage injury, or apophysitis. * recurrent patellar subluxation or dislocation. * cortisone use over an extended period of time. * previous surgery to the knee joint; trauma to the knee joint affecting the presenting clinical condition. * physiotherapy or other similar exercises for patellofemoral pain syndrome within the previous 3 months.
Where it's running
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Cairo
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Hafsa He Abdullah, MSc — Cairo University
- Study coordinator: Hafsa He Abdullah, MSc
- Email: Hafsahesham55@gmail.com
- Phone: 01007069080
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Taping methods with hip and knee strengthening for patellofemoral pain
This study tests whether McConnell taping or Kinesio taping, each with a guided hip and knee strengthening program, helps people aged 26-44 with patellofemoral pain.
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Tele-rehabilitation for patellofemoral pain in recreational athletes
A randomized trial tests whether a remote, app-guided exercise program can help recreational athletes with patellofemoral pain as well as traditional in-person physiotherapy.
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Kinesio Taping vs McConnell Taping for Patellofemoral Pain: Adding Taping to a Hip-Knee Exercise Program
This study tests whether Kinesio or McConnell taping, when added to a standardized hip-knee exercise plan, helps people 18–50 with patellofemoral pain more than exercise alone.
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Three Ways to Strengthen the VMO for Patellofemoral Pain
This study tests whether isometric, isotonic, or eccentric strengthening of the vastus medialis oblique (VMO) in the 0–30° knee bend helps reduce knee pain and improve function in adults with patellofemoral pain.
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Saphenous nerve release for patellofemoral (anterior knee) pain
This trial will try a manual saphenous nerve release to reduce pain and improve knee function and balance in adults 18–35 with patellofemoral pain who have a positive saphenous neurodynamic test.
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Myofascial release therapy for knee pain related to patellar tracking issues
This study is trying out a special massage technique to see if it can help young adults with knee pain from patellar tracking issues feel better and move more easily.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.