Clinical trial Recruiting at 1 site Interventional Ages 18 to 30

Popliteus muscle release versus Kinesio taping for patellofemoral pain

Official title: Popliteus Muscle Release Versus Kinesio Taping on Patellofemoral Pain Syndrome

Run by Cairo University · NCT07290296 · Data updated 2026-11-12

This will test whether popliteus muscle release or Kinesio taping better reduces pain and improves function in adults 18–30 with patellofemoral pain.

More Patellofemoral Pain Syndrome trials

Quick facts

Study typeInterventional
Ages18 Years to 30 Years
SexAll
Enrollment48 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJanuary 10, 2026
Main results expectedMay 2026
Study endsMay 2026
Registry record updatedMay 28, 2026
Trial IDNCT07290296 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–30 with at least three months of patellofemoral pain, worst-week pain ≥3/10, pain reproducible by activities like stairs or squatting, and a positive patellar compression or palpation test.

Probably not a fit

Patients with other specific knee pathology on imaging (osteoarthritis, meniscal, ligament, or cartilage injury), recurrent patellar dislocation, prior knee surgery, recent physiotherapy for patellofemoral pain syndrome, prolonged corticosteroid use, or acute knee trauma are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–30 with at least three months of patellofemoral pain and a minimum worst-week pain score of 3/10 will be enrolled. Participants will receive one of three interventions—popliteus muscle release, Kinesio taping, or standard physical therapy—and outcomes will include pain intensity, knee function, dynamic balance, and quadriceps strength. Pain will be measured with a visual analog scale and function, balance, and strength with standardized clinical and performance tests. The trial compares the short-term effects of a targeted soft-tissue release versus supportive taping when added to conventional care.

Why it matters

Potential benefit: If successful, the findings could identify a simple, non-surgical technique that reduces anterior knee pain and improves strength and balance.

How similar studies have gone: Systematic reviews suggest Kinesio taping can reduce pain as an adjunct to exercise and some reports support soft-tissue manipulation for knee pain, but direct head-to-head comparisons of popliteus release and taping are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of both genders with an age range of 18-30 years old.
* minimum 3-month history of patellofemoral pain.
* a pain score for worst pain intensity during the previous week of 3 or more on a Visual Analog Scale (0-10, most pain).
* reproduced by at least two of the following activities: Stair ascent or descent, hopping, running, prolonged sitting, squatting, or kneeling and present on at least one of the following clinical tests: Compression of the patella or palpation of the patellar facets.

Exclusion Criteria:

* Clinical, x-ray, or MRI findings indicative of other specific pathology, including osteoarthritis, meniscal, ligament, or cartilage injury, or apophysitis.
* recurrent patellar subluxation or dislocation.
* cortisone use over an extended period of time.
* previous surgery to the knee joint; trauma to the knee joint affecting the presenting clinical condition.
* physiotherapy or other similar exercises for patellofemoral pain syndrome within the previous 3 months.

Where it's running

  • Cairo
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.