Saphenous nerve release for patellofemoral (anterior knee) pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patellofemoral pain syndrome commonly causes anterior knee pain in young active adults and is usually treated with quadriceps and hip exercise programs. This interventional study targets a possible neural contributor by applying a manual saphenous nerve release to participants with a positive saphenous neurodynamic test. Eligible participants (age 18–35, BMI 18–25, anterior knee pain ≥6 weeks) will receive the nerve-focused manual therapy and be measured for changes in pain, knee function, and balance before and after the intervention. The work is conducted at the Faculty of Physical Therapy, Cairo University, as a supplement to conventional PFPS rehabilitation approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1 - Age from 18 to 35 and BMI 18 to 25 kg/m2. 2. Both gender (male and female) 3. Patients who had anterior knee pain for at least six weeks 4. Patients with positive saphenous neurodynamic test (SAPHNT)

Exclusion Criteria:

1. Knee replacement
2. An intraarticular injection within the past 3 months
3. Previous operative treatment or arthroscopy, other secondary knee-related problems (bursitis, tendinopathy, osteochondritis, neuromas, intraarticular pathology (such as osteoarthritis), tumor, and rheumatologic diseases
4. Diabetic neuropathic pain or fibromyalgia

Where it's running

• Faculty of Physical Therapy, Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Markos Boshra, bachelor's
• Email: markosboshra3@gmail.com
• Phone: 01201365245

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Taping methods with hip and knee strengthening for patellofemoral pain

  This study tests whether McConnell taping or Kinesio taping, each with a guided hip and knee strengthening program, helps people aged 26-44 with patellofemoral pain.

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• Tele-rehabilitation for patellofemoral pain in recreational athletes

  A randomized trial tests whether a remote, app-guided exercise program can help recreational athletes with patellofemoral pain as well as traditional in-person physiotherapy.

  Recruiting University of Faisalabad · Faisalābad, Punjan · NCT07693634

• Kinesio Taping vs McConnell Taping for Patellofemoral Pain: Adding Taping to a Hip-Knee Exercise Program

  This study tests whether Kinesio or McConnell taping, when added to a standardized hip-knee exercise plan, helps people 18–50 with patellofemoral pain more than exercise alone.

  Recruiting Cairo University · Beirut, Beirut · NCT07671482

• Three Ways to Strengthen the VMO for Patellofemoral Pain

  This study tests whether isometric, isotonic, or eccentric strengthening of the vastus medialis oblique (VMO) in the 0–30° knee bend helps reduce knee pain and improve function in adults with patellofemoral pain.

  Recruiting Firat University · Elâzığ, MErkez · NCT07562425

• Popliteus muscle release versus Kinesio taping for patellofemoral pain

  This will test whether popliteus muscle release or Kinesio taping better reduces pain and improves function in adults 18–30 with patellofemoral pain.

  Recruiting Cairo University · Cairo · NCT07290296

• Myofascial release therapy for knee pain related to patellar tracking issues

  This study is trying out a special massage technique to see if it can help young adults with knee pain from patellar tracking issues feel better and move more easily.

  Recruiting Riphah International University · Lahore, Punjab Province · NCT06875804

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.