Coping skills program using heart rate biofeedback for youth with inflammatory bowel disease

A Heart Rate Variability Biofeedback Enhanced Behavioral Intervention to Improve Psychological and Disease Functioning in Youth With Inflammatory Bowel Disease (IBD)

Not applicable Interventional Emory University · NCT06537258

This study is testing a new online program that helps teenagers with inflammatory bowel disease learn coping skills and manage their stress by using heart rate biofeedback.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment128 (estimated)
Ages13 Years to 18 Years
SexAll
SponsorEmory University Academic / other
Locations3 sites (Atlanta, Georgia and 2 other locations)
Trial IDNCT06537258 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a virtually delivered, group-based coping skills treatment program that incorporates heart rate variability biofeedback for youth aged 13-18 diagnosed with inflammatory bowel disease (IBD). Participants will be randomized into either a biofeedback enhanced treatment group or a wait-list control group. The study will involve surveys, chart reviews, blood sampling, and non-invasive assessments over a 7-month period, including four in-person visits and six virtual sessions. The goal is to address autonomic dysfunction associated with IBD through cognitive behavioral therapy techniques.

Who should consider this trial

Good fit: Ideal candidates are youth aged 13-18 with biopsy-confirmed IBD and experiencing symptoms of depression or anxiety.

Not a fit: Patients with developmental disabilities, other chronic diseases, or those on medications affecting autonomic function may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could improve coping strategies and overall well-being for youth suffering from inflammatory bowel disease.

How similar studies have performed: Other studies have shown promise in using biofeedback and cognitive behavioral therapy for managing chronic conditions, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis with biopsy-confirmed IBD for at least 4 months,
* ages 13 through 18 years inclusive,
* speak English,
* enrolling with at least 1 parent/guardian who is willing to participate by completing surveys,
* positive depression or anxiety screens using the PHQ-4, - access to home internet to participate in virtual intervention,
* youth and parent agree to the conditions of study participation, including randomization, participation in intervention, and follow-up assessments,
* youth is medically approved to engage in normal daily activities (e.g., attend school, extracurricular activities)

Exclusion Criteria:

* previous diagnosis of developmental disabilities that require full-time special education or that impair the ability to respond to treatment,
* diagnosis with any other chronic disease (e.g., diabetes, epilepsy, etc.),
* diagnosis of abnormal thyroid function,
* treatment with any drug with known autonomic cardiovascular influences including beta-blockers, central sympatholytic agents, or antidepressants.

Where this trial is running

Atlanta, Georgia and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Inflammatory Bowel Diseasescognitive behavioral therapyheart rate variability
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.