Comparing ventilation methods in young children during surgery

Comparison of Positive Pressure Ventilation Strategies in Young Children Undergoing Laparoscopic Inguinal Hernia Repair With Laryngeal Mask Airway: A Prospective Randomized Study

This study is testing different ways to help young children breathe during surgery to see which method works best for keeping their lungs stable.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 78 (estimated)
• Ages: 1 Year to 5 Years
• Sex: All
• Sponsor: Beni-Suef University (Academic / other)
• Locations: 1 site (Benisuef)
• Trial ID: NCT06612125 on ClinicalTrials.gov

What this trial studies

This study evaluates different strategies of positive pressure ventilation in children aged 1 to 5 years undergoing laparoscopic inguinal hernia repair. It compares volume-controlled ventilation (VCV), pressure-controlled ventilation (PCV), and pressure-controlled volume guaranteed ventilation (PCV-VG) to determine the most effective method for ensuring stable ventilation. The use of a laryngeal mask airway (LMA) is emphasized for its advantages in minimizing airway irritation. The goal is to improve respiratory management during pediatric anesthesia.

Who should consider this trial

Good fit: Ideal candidates are children aged 1 to 5 years scheduled for laparoscopic inguinal hernia repair with a physical status classification of I-II.

Not a fit: Patients with cardiopulmonary disease, severe hepatorenal dysfunction, or other specified exclusions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance ventilation strategies in pediatric patients, leading to better surgical outcomes and reduced complications.

How similar studies have performed: Other studies have explored various ventilation strategies, but this specific comparison in pediatric patients is relatively novel.

Eligibility criteria

Inclusion Criteria:

1. age between 1 and 5 years.
2. patient scheduled for laparoscopic inguinal hernia repair.
3. American Society of Anesthesiologists classification of physical status of I-II.

Exclusion Criteria:

1. cardiopulmonary disease.
2. severe hepatorenal dysfunction.
3. history of upper respiratory tract infection 2 weeks before the operation.
4. overweight \[more than 20% of standard body weight\].
5. neuromuscular disease.
6. anticipated difficult airway.
7. hiatus hernia or gastroesophageal reflux disease.

Where this trial is running

Benisuef

• Benisuef university hospital — Benisuef, Egypt (Recruiting)

Study contacts

• Principal investigator: Mariana as Mansour, MD — benisuef university hospital Egypt
• Study coordinator: Mariana AS Mansour, MD

Conditions Ventilation Therapy; Complications