Comparing two ventilation modes for ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness of two mechanical ventilation modes, Synchronized Intermittent Mandatory Ventilation (SIMV) and Mandatory Minute Ventilation (MMV), in adult ICU patients who are hemodynamically stable. The study utilizes Electrical Impedance Tomography (EIT) to monitor lung ventilation and perfusion in real-time, allowing for a detailed comparison of the physiological impacts of each ventilation mode. Patients will switch between SIMV and MMV to assess which mode provides better respiratory support without the need for investigational interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years

Intubated and receiving invasive mechanical ventilation

Hemodynamically stable (no vasopressor support)

FiO₂ ≤ 60%

PEEP ≤ 8 cmH₂O

Not receiving neuromuscular blocking agents

Able to tolerate switching between SIMV and MMV modes

Exclusion Criteria:

Pregnant or breastfeeding patients

Patients with neuromuscular diseases affecting respiratory drive

Unstable hemodynamics or ongoing need for vasopressors

Patients requiring high PEEP (\>8 cmH₂O)

Patients with DNR (do not resuscitate) status

Participation in another interventional study

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Where it's running

• Harran University Faculty of Medicine, Department of Anesthesiology and Reanimation
  Sanliurfa, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: MELAHAT YALÇIN SOLAK, Medical Doctor
• Email: melosyalcin@gmail.com
• Phone: +905326479195

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.