Comparing two types of pain relief techniques for surgery

Ultrasound Guided Modified Versus Conventional Serratus Anterior Plane Block as a Preemptive Analgesia for Unilateral Video-Assisted Thoracoscopic Surgery

Not applicable Interventional Zagazig University · NCT05661253

This study is testing which of two pain relief methods works better for patients having surgery on their lungs to help them feel less pain and use fewer opioids afterward.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment99 (estimated)
Ages21 Years to 60 Years
SexAll
SponsorZagazig University Government
Locations1 site (Zagazig)
Trial IDNCT05661253 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of preemptive analgesia using an ultrasound-guided modified serratus anterior plane block against a conventional ultrasound-guided serratus anterior plane block in patients undergoing Video-Assisted Thoracoscopic Surgery. The focus is on assessing postoperative pain relief and opioid consumption. By utilizing two different techniques, the study aims to determine which method provides better pain management outcomes for patients. The interventions involve administering 25 ml of bupivacaine 0.25% through each technique.

Who should consider this trial

Good fit: Ideal candidates are adults aged 21-70 with a BMI of 18-30, scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery.

Not a fit: Patients with a history of chronic pain, those on anticoagulant therapy, or individuals with significant comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and reduced opioid use for patients undergoing thoracic surgery.

How similar studies have performed: Other studies have shown promising results with similar analgesic techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient consent.
* both sex.
* Age: 21-70 years old.
* BMI: 18- 30 kg/m2
* ASA: I and II.
* Scheduled for elective unilateral Video-Assisted thoracoscopy under general anesthesia.

Exclusion Criteria:

* History of allergy to the local anesthesia agents used in this study,
* Skin lesion at needle insertion site,
* Those receiving anticoagulant therapy or having bleeding disorders
* Patients with history of chronic pain and taking analgesics,
* Patients with sepsis and Significant cardiac, liver or renal diseases
* Uncooperative patients or with psychiatric disorders.

Where this trial is running

Zagazig

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative Pain, Acute
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.