Comparing two surgical methods for treating periodontitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two surgical approaches, Modified Widman Flap and Fiber Retention Osseous Resective Surgery, in treating periodontitis. The study focuses on patients with residual periodontal pockets after initial treatment steps, aiming to reduce the risk of disease progression and tooth loss. Participants will undergo one of the two surgical interventions to assess which method yields better outcomes in terms of pocket depth and overall periodontal health.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years;
* Patients affected by periodontitis;
* No systemic disease or pregnancy;
* No systemic antibiotic therapy in 6 months preceding the enrollment;
* Smoking ≤ 20 cigarettes/day;
* Full-mouth plaque score (FMPS) and full- mouth bleeding score (FMBS) ≤ 15%;
* Residual periodontal pocket ≥5 mm with bleeding on probing at posterior natural teeth;
* Experimental pocket associated with a detectable infrabony defect ≤ 3mm at x-ray;
* No history of periodontal surgery at the experimental site.

Exclusion Criteria:

* Undetectable cemento-enamel junction (CEJ) at experimental teeth;
* Severe furcation involvement (class II and III);
* Abutment for prosthetic rehabilitation;
* Periodontal Pockets associated with infrabony defect \>3 mm;
* Horizontal bone loss higher than 1/3 of the root length at experimental teeth;
* Severe tooth mobility at baseline (class 2 or 3).

Where it's running

• Università degli Studi di Firenze
  Florence, Fi, Italy Recruiting

Study contacts

• Study coordinator: Luigi Barbato, Dr.
• Email: luigi.barbato@unifi.it
• Phone: 3299457556

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hyaluronic acid and octenidine gel with non-surgical gum treatment

  This pilot will test whether adding a hyaluronic acid and octenidine gel to non-surgical periodontal treatment helps adults with advanced periodontitis heal faster and reduce inflammation.

  Recruiting at 2 sites Queen Mary University of London · London and 1 other locations · NCT06522438

• Dental Loupes vs. Dental Operating Microscope for Non-Surgical Periodontal Treatment

  This study tests whether using dental loupes or a dental operating microscope makes non-surgical periodontal cleaning more effective for adults with periodontitis.

  Recruiting Saglik Bilimleri Universitesi · Ankara and 2 other locations · NCT07822269

• JAK1 and JAK2 activation in healthy versus inflamed gums

  We will test whether the JAK1 and JAK2 immune-signaling pathways are more active in adults with periodontitis than in adults with healthy gums.

  Recruiting University of Chile · Santiago, Metropolitan Region · NCT07536204

• Platelet-rich fibrin added to deep tooth cleaning for periodontitis

  This will try adding platelet-rich fibrin (PRF) to deep non-surgical cleaning to see if it improves gum healing and attachment in adults with stage II–IV periodontitis.

  Recruiting University of Bern · Bern · NCT07013682

• Comparing three types of papilla incision techniques in periodontal surgery

  This study is testing three different ways to make cuts in the gums during periodontal surgery to see which method works best for treating gum disease.

  Recruiting Universidad de Murcia · Murcia, Murcia · NCT06428149

• Treatment of gum defects using hyaluronic acid and polynucleotides

  This study is testing if adding a special gel to gum surgery helps people with gum disease heal better and faster.

  Recruiting at 2 sites Queen Mary University of London · London and 1 other locations · NCT06309719

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.