Comparing two pain management techniques for kidney removal surgery
The Comparison of Erector Spinae Plane Block and Quadratus Lumborum Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Nephrectomy: A Randomized, Prospective, Controlled Study
This study is testing which of two pain relief methods works better for people having kidney removal surgery to help them feel less pain afterward.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Istanbul Medipol University Hospital Academic / other |
| Locations | 1 site (Istanbul, Bağcılar) |
| Trial ID | NCT06298227 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of two ultrasound-guided regional anesthesia techniques, the Erector Spinae Plane Block (ESPB) and the Quadratus Lumborum Block (QLB), for managing postoperative pain in patients undergoing laparoscopic nephrectomy. The ESPB is performed at the T11 level, while the QLB is performed at the L1-L2 level, both aiming to provide effective analgesia after surgery. The study will assess pain control outcomes and opioid consumption in patients receiving these interventions. By evaluating these two methods, the study seeks to identify the most effective approach for pain management in this surgical context.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals classified as ASA I-II who are scheduled for living donor laparoscopic nephrectomy under general anesthesia.
Not a fit: Patients with a history of bleeding disorders, those on anticoagulant therapy, or individuals with allergies to local anesthetics or opioids may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative pain management for patients undergoing laparoscopic nephrectomy, potentially reducing opioid use and enhancing recovery.
How similar studies have performed: Previous studies have shown promising results with both ESPB and QLB for postoperative pain management, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) classification I-II * Scheduled for living donor laparoscopic nephrectomy under general anesthesia Exclusion Criteria: * history of bleeding diathesis, * receiving anticoagulant treatment, * known local anesthetics and opioid allergy, * infection of the skin at the site of the needle puncture, * pregnancy or lactation, * patients who refuse the procedure or participation in the study
Where this trial is running
Istanbul, Bağcılar
- Istanbul Medipol University Mega Hospital Complex — Istanbul, Bağcılar, Turkey (Recruiting)
Study contacts
- Study coordinator: Ayşe İnce, Assist Prof, MD
- Email: drayseince@gmail.com
- Phone: +905366774988
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.