Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Comparing two non-surgical treatments for peri-implantitis

Official title: Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis: Mechanical Debridement vs. Air-polishing

Run by Tannhelsetjenestens Kompetansesenter for Nord-Norge · NCT05683405 · Data updated 2026-11-12

This study is testing which of two non-surgical treatments for peri-implantitis—mechanical cleaning or air-polishing—works better to improve gum health around dental implants.

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment88 (estimated)
SponsorTannhelsetjenestens Kompetansesenter for Nord-Norge
Academic / other
Locations1 site (Tromsø, Troms)
StatusRecruiting
StartedAugust 1, 2023
Main results expectedAugust 2026
Study endsDecember 2028
Registry record updatedJune 1, 2023
Trial IDNCT05683405 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals referred for treatment of peri-implantitis who have at least one implant affected by the condition.

Probably not a fit

Patients with cemented prosthetic reconstructions, those smoking more than 10 cigarettes per day, or individuals with poorly controlled diabetes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two non-surgical treatments for peri-implantitis: mechanical debridement and air-polishing using the Perioflow® device. Participants will receive one of the two treatments, and researchers will evaluate the outcomes by measuring pocket depth and bleeding on probing. The goal is to determine which method provides better results in managing peri-implantitis. This study is being conducted at Tannhelsetjenestens kompetansesenter for Nord-Norge.

Why it matters

Potential benefit: If successful, this study could lead to more effective non-surgical treatment options for patients with peri-implantitis.

How similar studies have gone: While there have been studies on non-surgical treatments for peri-implantitis, the specific comparison of air-polishing versus mechanical debridement is less common, making this approach somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Referred to TkNN (Tannhelsetjenestens kompetansesenter for Nord-Norge) for treatment of peri-implantitis
* Participants should have at least one implants with peri-implantitis according to the diagnostic criteria from the 2017 Chicago Consensus Meeting.

Exclusion Criteria:

* Cemented prosthetic reconstructions, individuals smoking more than 10 cigarettes per day, individuals with diabetes and poor control of blood glucose levels, antibiotic treatment during the past threee months, and implants that are preferably to be extracted due to prognosis or function, are excluded.

Where it's running

  • Tannhelsetjenestens kompetansesenter for Nord-Norge
    Tromsø, Troms, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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    This study tests how smoking changes the body's immune response around dental implants in people with healthy implants, peri-implant mucositis, or peri-implantitis.

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  • AmbiJet-assisted treatment for inflamed dental implants

    This study tests whether applying cold atmospheric plasma with the AmbiJet system after standard cleaning helps reduce inflammation around dental implants more quickly in adults with peri-implant mucositis or peri-implantitis.

    Recruiting Freiburger Medizintechnik GmbH · Romny · NCT07722715

  • Non-surgical H42 treatment for peri-implant pockets

    This study tests whether H42 can help heal peri-implant pockets compared with no-H42 care in adults with 6–8 mm pockets.

    Recruiting Bioteck S.p.A. · Seville · NCT07680491

  • Macrophage behavior around dental implants in health and peri-implantitis

    This study will test whether macrophage-related markers in tissue and fluids around dental implants differ between people with peri-implantitis and those with healthy implants, and whether smoking changes those markers.

    Recruiting Biruni University · Istanbul · NCT07569432

  • Access to probing around dental implants

    This multicenter study tests whether limited access to peri-implant probing is linked to more bone loss around dental implants in adults with implants in use for at least three years.

    Recruiting at 9 sites Arrow Development · A Coruña, A Coruña and 8 other locations · NCT07557459

  • Two surgical treatments for peri-implantitis: implantoplasty versus mechanical debridement

    This tests whether adding implantoplasty to resective surgery reduces inflammation and improves outcomes around dental implants in adults with peri-implantitis.

    Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07550127

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.