Comparing two non-surgical treatments for peri-implantitis
Official title: Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis: Mechanical Debridement vs. Air-polishing
Run by Tannhelsetjenestens Kompetansesenter for Nord-Norge · NCT05683405 · Data updated 2026-11-12
This study is testing which of two non-surgical treatments for peri-implantitis—mechanical cleaning or air-polishing—works better to improve gum health around dental implants.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 88 (estimated) |
| Sponsor | Tannhelsetjenestens Kompetansesenter for Nord-Norge Academic / other |
| Locations | 1 site (Tromsø, Troms) |
| Status | Recruiting |
| Started | August 1, 2023 |
| Main results expected | August 2026 |
| Study ends | December 2028 |
| Registry record updated | June 1, 2023 |
| Trial ID | NCT05683405 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals referred for treatment of peri-implantitis who have at least one implant affected by the condition.
✕Probably not a fit
Patients with cemented prosthetic reconstructions, those smoking more than 10 cigarettes per day, or individuals with poorly controlled diabetes may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the effectiveness of two non-surgical treatments for peri-implantitis: mechanical debridement and air-polishing using the Perioflow® device. Participants will receive one of the two treatments, and researchers will evaluate the outcomes by measuring pocket depth and bleeding on probing. The goal is to determine which method provides better results in managing peri-implantitis. This study is being conducted at Tannhelsetjenestens kompetansesenter for Nord-Norge.
Why it matters
Potential benefit: If successful, this study could lead to more effective non-surgical treatment options for patients with peri-implantitis.
How similar studies have gone: While there have been studies on non-surgical treatments for peri-implantitis, the specific comparison of air-polishing versus mechanical debridement is less common, making this approach somewhat novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Referred to TkNN (Tannhelsetjenestens kompetansesenter for Nord-Norge) for treatment of peri-implantitis * Participants should have at least one implants with peri-implantitis according to the diagnostic criteria from the 2017 Chicago Consensus Meeting. Exclusion Criteria: * Cemented prosthetic reconstructions, individuals smoking more than 10 cigarettes per day, individuals with diabetes and poor control of blood glucose levels, antibiotic treatment during the past threee months, and implants that are preferably to be extracted due to prognosis or function, are excluded.
Where it's running
-
Tannhelsetjenestens kompetansesenter for Nord-Norge
Tromsø, Troms, Norway Recruiting
Study contacts
- Study coordinator: Elin Hadler-Olsen, PhD
- Email: elin.hadlerolsen@tffk.no
- Phone: +47 48 06 72 49
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How Smoking Affects Immune Responses Around Dental Implants
This study tests how smoking changes the body's immune response around dental implants in people with healthy implants, peri-implant mucositis, or peri-implantitis.
-
AmbiJet-assisted treatment for inflamed dental implants
This study tests whether applying cold atmospheric plasma with the AmbiJet system after standard cleaning helps reduce inflammation around dental implants more quickly in adults with peri-implant mucositis or peri-implantitis.
-
Non-surgical H42 treatment for peri-implant pockets
This study tests whether H42 can help heal peri-implant pockets compared with no-H42 care in adults with 6–8 mm pockets.
-
Macrophage behavior around dental implants in health and peri-implantitis
This study will test whether macrophage-related markers in tissue and fluids around dental implants differ between people with peri-implantitis and those with healthy implants, and whether smoking changes those markers.
-
Access to probing around dental implants
This multicenter study tests whether limited access to peri-implant probing is linked to more bone loss around dental implants in adults with implants in use for at least three years.
-
Two surgical treatments for peri-implantitis: implantoplasty versus mechanical debridement
This tests whether adding implantoplasty to resective surgery reduces inflammation and improves outcomes around dental implants in adults with peri-implantitis.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.