Comparing two nerve blocks for pain management after hip replacement surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the pericapsular nerve block compared to the fascia iliaca nerve block for managing postoperative pain in adults undergoing total hip arthroplasty. It is a single-center, randomized, controlled trial where participants will receive one of the two nerve block regimens as part of their standard care. The goal is to improve pain management, enhance recovery, and reduce complications associated with inadequate pain control after surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Planned primary total hip arthroplasty with anterior (Smith-Peterson) approach
* ASA score of 1 to 3
* Indicated for one of the two nerve block groups
* Must be opioid naïve at screening as defined by the FDA - According to the Food and Drug Administration, opioid-tolerant patients were those currently receiving or who had previously received 60 mg PO morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg PO oxycodone per day, 8 mg PO hydromorphone per day, 25 mg PO oxymorphone per day, 60 mg PO hydrocodone per day, or an equivalent dose of another opioid for a duration of one week or longer (16)

Exclusion Criteria:

* Current or previous diagnosis of "chronic pain"
* Opioid tolerant at time of screening (for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid.)
* Diagnosis of ankylosing spondylitis
* Allergy to any potential medications utilized in any of the two groups
* Conversion of patient to general anesthesia intraoperatively
* Treatment with another investigational drug or other intervention for pain
* Any condition(s) or diagnosis, both physical or psychological, or physical exam finding in the opinion of the investigator that would precludes participation

Where it's running

• Sinai Hospital of Baltimore
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Ronald Delanois, MD — LifeBridge Health
• Study coordinator: Martin Gesheff
• Email: mgesheff@lifebridgehealth.org
• Phone: 410-601-9467

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Dexmedetomidine during hip replacement to modulate nerves and inflammation

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• VR After Hip Replacement: See if Virtual Reality Helps Pain and Comfort

  This study tests whether virtual reality can help adults recover after total hip replacement by reducing pain and anxiety and improving comfort.

  Recruiting Adiyaman University · Malatya · NCT07689461

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.