Comparing two methods for hip pain relief after surgery
A Randomized Comparison Between Total Periarticular Anesthetic Infiltration and Partial Posterior Periarticular Anesthetic Infiltration Plus Low Volume Ultrasound-Guided Pericapsular Nerve Group Block for Total Hip Replacement Analgesia
This study is testing two different ways to relieve hip pain after surgery to see which one helps patients feel better without affecting their ability to move.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 74 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of Chile Academic / other |
| Locations | 1 site (Santiago, Santiago Metropolitan) |
| Trial ID | NCT06075004 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of total periarticular infiltration (PAI) versus a combination of posterior periarticular infiltration and pericapsular nerve group block (PENGB) for managing pain after total hip arthroplasty. Patients will be randomly assigned to one of the two treatment groups, and outcome assessors will be blinded to the treatment received. The interventions will be performed by an expert orthopedic surgeon anesthesiologist in a controlled operating room environment, ensuring standardized conditions for all participants. The study seeks to determine which method provides better pain control while minimizing motor compromise during early rehabilitation.
Who should consider this trial
Good fit: Ideal candidates for this study are adults classified as American Society of Anesthesiologists 1-3 with a body mass index between 20 and 35.
Not a fit: Patients with pre-existing neuropathy, coagulopathy, renal or hepatic failure, allergies to local anesthetics or morphine, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing hip replacement surgery, facilitating quicker recovery and rehabilitation.
How similar studies have performed: Previous studies have shown promising results with similar nerve block techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists classification 1-3 * Body mass index between 20 and 35 (kg/m2) Exclusion Criteria: * Adults who are unable to give their own consent * Pre-existing neuropathy (assessed by history and physical examination) * Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50) * Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. creatinine ≥ 100) * Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. transaminases ≥ 100) * Allergy to local anesthetics (LAs) or morphine * Pregnancy * Prior surgery in the inguinal area corresponding surgical side * Chronic pain syndromes requiring opioid intake at home
Where this trial is running
Santiago, Santiago Metropolitan
- Hospital Clínico Universidad de Chile — Santiago, Santiago Metropolitan, Chile (Recruiting)
Study contacts
- Principal investigator: Daniela Bravo, MD — University of Chile
- Study coordinator: Daniela Bravo, MD
- Email: dbravoadvis@uchile.cl
- Phone: 569222878209
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.