Comparing two methods for hip pain relief after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of total periarticular infiltration (PAI) versus a combination of posterior periarticular infiltration and pericapsular nerve group block (PENGB) for managing pain after total hip arthroplasty. Patients will be randomly assigned to one of the two treatment groups, and outcome assessors will be blinded to the treatment received. The interventions will be performed by an expert orthopedic surgeon anesthesiologist in a controlled operating room environment, ensuring standardized conditions for all participants. The study seeks to determine which method provides better pain control while minimizing motor compromise during early rehabilitation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* American Society of Anesthesiologists classification 1-3
* Body mass index between 20 and 35 (kg/m2)

Exclusion Criteria:

* Adults who are unable to give their own consent
* Pre-existing neuropathy (assessed by history and physical examination)
* Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50)
* Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. creatinine ≥ 100)
* Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work-up i.e. transaminases ≥ 100)
* Allergy to local anesthetics (LAs) or morphine
* Pregnancy
* Prior surgery in the inguinal area corresponding surgical side
* Chronic pain syndromes requiring opioid intake at home

Where it's running

• Hospital Clínico Universidad de Chile
  Santiago, Santiago Metropolitan, Chile Recruiting

Study contacts

• Principal investigator: Daniela Bravo, MD — University of Chile
• Study coordinator: Daniela Bravo, MD
• Email: dbravoadvis@uchile.cl
• Phone: 569222878209

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.