Ultrasound-guided lung recruitment to prevent postoperative lung complications after total laparoscopic hysterectomy in people with obstructive sleep apnea
Effects of Ultrasound-guided Recruitment Manoeuvres on Postoperative Pulmonary Complications in OSA Patients Undergoing Total Laparoscopic Hysterectomy
This trial will test whether ultrasound-guided lung recruitment maneuvers can reduce postoperative pulmonary complications in adults with obstructive sleep apnea having total laparoscopic hysterectomy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | The First Affiliated Hospital of Xinxiang Medical College Academic / other |
| Locations | 1 site (Xinxiang, Henan) |
| Trial ID | NCT07362680 on ClinicalTrials.gov |
What this trial studies
Adults with obstructive sleep apnea who meet BMI and STOP-BANG criteria and are scheduled for elective total laparoscopic hysterectomy will receive one of three intraoperative lung recruitment strategies: sustained inflation, incremental PEEP, or ultrasound-guided recruitment. Investigators will compare postoperative pulmonary complications, including atelectasis, and will use end-expiratory lung volume (EELV) measurements to judge how effectively each maneuver re-expands the lung. The ultrasound-guided arm uses bedside lung ultrasound to guide recruitment delivery and to detect residual consolidation. The protocol focuses on short-term respiratory outcomes and the practicality of using EELV as an effectiveness metric.
Who should consider this trial
Good fit: Adults (≥18 years) with BMI >28 kg/m², STOP-BANG score ≥3, ASA I–III who are scheduled for elective total laparoscopic hysterectomy are the intended participants.
Not a fit: Patients with pre-existing severe pulmonary disease, abnormal preoperative chest imaging, severe cardiac arrhythmias, prior cardiac surgery, or allergies to study medications are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, ultrasound-guided recruitment could reduce postoperative atelectasis and other lung complications, improving breathing recovery after laparoscopic hysterectomy in OSA patients.
How similar studies have performed: Recruitment maneuvers have reduced atelectasis and improved oxygenation in other surgical populations, but ultrasound-guided recruitment with EELV monitoring is relatively novel for OSA patients undergoing laparoscopic hysterectomy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years; * Scheduled for elective total laparoscopic hysterectomy; * American Society of Anesthesiologists (ASA) I to III; * BMI \> 28 kg/m²; * STOP-BANG score ≥ 3. Exclusion Criteria: * Abnormal findings on preoperative chest X-ray or CT, such as atelectasis, pneumothorax, thoracic deformity, pleural effusion, or neuromuscular diseases; * Pre-existing severe pulmonary diseases; * Severe cardiac arrhythmias or a history of cardiac surgery; * Allergy to any medications used in the study.
Where this trial is running
Xinxiang, Henan
- The First Affiliated Hospital of Xinxiang Medical College — Xinxiang, Henan, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.