Comparing spinal anesthesia and general anesthesia for patients with sepsis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness and safety of continuous spinal anesthesia compared to general anesthesia in patients diagnosed with sepsis. It focuses on the challenges posed by hemodynamic instability in septic patients, who may experience increased risks of hypotension with conventional spinal anesthesia. By using a smaller dose of local anesthetic, the study aims to minimize hypotension while effectively managing anesthesia during surgical procedures. The trial will include patients who are hemodynamically stable and suitable for spinal anesthesia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients over 21 years old
* American Society of Anesthesiologists (III, IV) diagnosed with sepsis (Sequential Organ Failure Assessment (SOFA) score ≥ 7)
* Hemodynamically stable and not on vasopressor due to lower limb pathology candidate for spinal anesthesia to drain source of infection.

Exclusion Criteria:

* Patients with known hypersensitivity to local anesthesia.
* Infection at the site of injection.
* Coagulopathy.
* Septic shock.
* Increase of intracranial pressure.
* Severe deformity of the spinal column.

Where it's running

• Tanta University Hospitals
  Tanta, Elgharbia, Egypt Recruiting

Study contacts

• Study coordinator: Mahmoud R Ahmed, M.B.B.CH
• Email: mahmoud162104_pg@med.tanta.edu.eg
• Phone: +20 102 432 0926

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.