Comparing scar outcomes from different incision techniques in mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the cosmetic outcomes of surgical incisions made with scalpel, electrocautery, and PEAK PlasmaBlade during total mastectomy procedures without immediate breast reconstruction. It is a double-blind, prospective randomized controlled trial involving patients scheduled for mastectomy, where scar cosmesis will be assessed at multiple postoperative intervals by independent observers. The aim is to determine if there are significant differences in scar appearance between the three incision methods, potentially guiding future surgical practices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients having a total mastectomy with or without axilla surgical staging

Exclusion Criteria:

* Patients having immediate breast reconstruction
* Patients with a diagnosis of inflammatory breast cancer
* History of keloid scar formation
* History of connective tissue disorder (scleroderma or rheumatoid arthritis with skin involvement)
* Patients with prior incision at the planned mastectomy site.
* Patients with known suture hypersensitivity
* Patients with evidence of current infection

Where it's running

• Mount Saint Joseph Hospital
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Carol K Dingee, MD, FRCSC — Providence Health Care, University of British Columbia
• Study coordinator: Carol K Dingee, MD, FRCSC
• Email: cdingee2@providencehealth.bc.ca
• Phone: 6048741141

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Preoperative Fasting to Shape the Gut with Hip Replacement

  This trial tests whether a 20-day preoperative fasting plan can lower inflammatory signals and broaden gut microbes in adults undergoing total hip arthroplasty.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT07651462

• Can infrared thermography help predict how skin wounds heal after surgery?

  This study tests if a harmless infrared camera can spot early signs of wound problems after skin surgery so clinicians can act sooner.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams Brabant · NCT07524062

• Lower leg skin grafts after tumour removal: does negative pressure dressings help or not?

  This trial tests whether negative pressure wound therapy over split-thickness skin grafts on the lower leg reduces infection compared with traditional dressings in adults after skin tumour removal.

  Recruiting Region Skane · Malmö · NCT07040683

• Improving respiratory care for patients having high-risk abdominal surgery

  This study is testing whether using a special mouthwash and different amounts of oxygen before surgery can help reduce the chances of pneumonia and infections in patients having major abdominal surgery.

  Recruiting at 34 sites Phase 3 University of Birmingham · Botucatu, São Paulo and 36 other locations · NCT04256798

• Antibiotic Tissue Penetration in Head and Neck Infection and Reconstructive Surgery

  This study tests how well common antibiotics reach head and neck tissue in adults with neck infections or during nasal reconstructive surgery using a flap.

  Recruiting Phase 4 Aarhus University Hospital · Aarhus N · NCT07896239

• Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery

  Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.

  Recruiting Semmelweis University · Budapest · NCT07896174

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.