Comparing PECS II nerve block and local anesthetic for pain control after breast cancer surgery
PECS II Blockade vs. Local Anesthesia: Postoperative Pain Control in Opioid-Free Oncologic Breast Surgery
This study is testing whether a new type of nerve block can help women feel less pain after breast cancer surgery compared to a regular local anesthetic.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 134 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Female |
| Sponsor | Faculdade de Ciências Médicas de Minas Gerais Academic / other |
| Locations | 1 site (Itabira, Minas Gerais) |
| Trial ID | NCT06889870 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of the PECS II interfascial nerve block compared to local anesthetic infiltration for managing postoperative pain in women undergoing breast cancer surgery. It is a prospective, randomized, double-blind study involving 133 female patients aged 18 to 80 years, who will be divided into two groups: one receiving the PECS II block and the other receiving local anesthetic infiltration. The study aims to assess pain levels, nausea, opioid consumption, and side effects in the 24 hours following surgery. The interventions will be performed after the induction of opioid-free/sparing general anesthesia.
Who should consider this trial
Good fit: Ideal candidates are female patients aged 18 to 80 years, classified as ASA physical status I, II, or III, undergoing unilateral breast surgery.
Not a fit: Patients who may not benefit include those who are pregnant, morbidly obese, have cognitive impairments, coagulopathies, allergies to local anesthetics, or a history of chronic pain or drug addiction.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and reduced opioid use for patients undergoing breast cancer surgery.
How similar studies have performed: Other studies have shown promising results with similar nerve block techniques for pain management, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:Female patients aged between 18 and 80 years, ASA physical status I, II or III and undergoing unilateral surgery. \- Exclusion Criteria: pregnant women, morbidly obese (BMI\>40 kg/m²), patients with cognitive impairment or inability to communicate with the evaluator, coagulopathies, history of allergy to local anesthetics and patients with a history of chronic pain or drug addiction. \-
Where this trial is running
Itabira, Minas Gerais
- Hospital Nossa Senhora das Dores — Itabira, Minas Gerais, Brazil (Recruiting)
Study contacts
- Study coordinator: Alessandra H De Souza, PhD
- Email: alessandra.souza@cienciasmedicasmg.edu.br
- Phone: 55-31984205240
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.