Comparing patients with and without endocarditis undergoing valve surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare patients with infective endocarditis to those without, who are undergoing cardiothoracic valve surgery. The investigators will evaluate various factors such as perioperative coagulation abnormalities, transfusion needs, and complications like thromboembolic events and mortality rates. By analyzing these differences, the study seeks to optimize perioperative care for high-risk patients with endocarditis. The research will also consider the impact of the specific pathogens causing endocarditis on patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \> 18 years
* Dutch or English speaking
* All patients with infective endocarditis admitted to Amsterdam UMC in the study period
* All patients with infective endocarditis scheduled for cardiac valve surgery compared to a matched cohort of patients scheduled for similar surgery due to non-infectious indication in Amsterdam UMC in the same period

Exclusion Criteria:

* Previous history of coagulation disorders

Where it's running

• Academic Medical Center
  Amsterdam, North Holland, Netherlands Recruiting

Study contacts

• Principal investigator: Markus W Hollmann, MD,PhD,PhD — Amsterdam Academic Medical Center
• Study coordinator: Jennifer S Breel, MPA,MSc
• Email: j.s.breel@amsterdamumc.nl
• Phone: +31610019257

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.