Comparing non-invasive and invasive hemodynamic assessments in heart failure patients
Noninvasive Versus Invasive Assessment of Hemodynamics in the Cardiac Intensive Care Unit
This study is testing whether non-invasive tests like ultrasound can give similar information about heart function as traditional invasive tests in patients with heart failure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Health Network, Toronto Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT06330597 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare non-invasive hemodynamic assessments using transthoracic echocardiography (TTE) and lung ultrasound (LUS) with traditional invasive assessments using pulmonary artery catheter (PAC) in patients with heart failure. Patients admitted to the Cardiac Intensive Care Unit (CICU) who have undergone PAC insertion will participate in the study. Each patient will receive TTE and LUS assessments immediately after the initial PAC assessment and daily thereafter. The goal is to better understand hemodynamic changes and improve patient management in heart failure.
Who should consider this trial
Good fit: Ideal candidates for this study are patients admitted to the CICU who have a PAC inserted as part of their standard care.
Not a fit: Patients currently enrolled in another trial with an active treatment arm may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of hemodynamic monitoring in heart failure patients, potentially leading to better treatment outcomes.
How similar studies have performed: Other studies have indicated the potential benefits of non-invasive hemodynamic monitoring, but this specific approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with admitted to the CICU in whom PAC is inserted as standard of care, Exclusion Criteria: * Enrollment into another trial with an active treatment arm
Where this trial is running
Toronto, Ontario
- University Health Network — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Filio Billia, MD PhD — Uhn
- Study coordinator: Yishay Szekely, MD
- Email: Yishay.szekely@uhn.ca
- Phone: 416-340-4800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.